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180-210 / 1000+ results![Reply to: Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation](/images/research/810d731b-249c-469e-ae71-a891e5b9477b/small/4706.jpg)
research Reply to: Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation
Low-dose oral minoxidil effectively treats mild-moderate male hair loss, alone or combined with other therapies.
![Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia](/images/research/2eb4c36c-228a-4dd0-ba26-f6a6a52e17ab/small/13511.jpg)
research Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia
Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.
![Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction](/images/research/ac0c13c1-a57f-4a2e-b94a-ca835d01570a/small/18221.jpg)
research Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
![Combination Therapy With Finasteride and Low-Dose Dutasteride in the Treatment of Androgenetic Alopecia](/images/research/399e4d14-e7a8-4c07-bccd-9b6b775e4e72/small/3272.jpg)
research Combination Therapy With Finasteride and Low-Dose Dutasteride in the Treatment of Androgenetic Alopecia
Finasteride and low-dose dutasteride combo improves hair growth and reduces hair loss with no major side effects.
![Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia](/images/research/cfc515ca-1859-48ee-b3a7-3860204fabb2/small/3871.jpg)
research Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia
Dutasteride is safe and effective for treating hair loss, but may decrease libido.
![Clinical Effects and Economic Impact of Dutasteride and Finasteride Therapy in Italian Men with Lower Urinary Tract Symptoms](/images/research/4e332b06-e5ec-4f4f-92f9-527da26c5958/small/3380.jpg)
research Clinical Effects and Economic Impact of Dutasteride and Finasteride Therapy in Italian Men with Lower Urinary Tract Symptoms
Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.
![Long-Term Safety and Efficacy of Mirabegron and Solifenacin in Combination Compared with Monotherapy in Patients with Overactive Bladder: SYNERGY II Study](/images/research/0964deb3-d491-41e7-a068-053231c2ad61/small/12181.jpg)
research Long-Term Safety and Efficacy of Mirabegron and Solifenacin in Combination Compared with Monotherapy in Patients with Overactive Bladder: SYNERGY II Study
Using mirabegron and solifenacin together is safe and more effective for treating overactive bladder than using either drug alone.
research Hair Regrowth in Endocrine Therapy Alopecia With Dutasteride Treatment in Women With Estrogen Positive Breast Cancer
![Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors](/images/research/00bd2098-6cdf-4860-ac61-fce7b4586044/small/3154.jpg)
research Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors
Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
![Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials](/images/research/47fca334-c750-4f4e-89e5-c0197e65b2fe/small/18409.jpg)
research Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
research Role of 5α-Reductase Inhibitors in Benign Prostatic Diseases
5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.
![Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide](/images/research/7311202d-9c82-402c-8e8b-e7ef6147dff9/small/17350.jpg)
research Optimal Management of Frontal Fibrosing Alopecia: A Practical Guide
Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.
research 5-Alpha-Reductase Inhibitor Treatment for Frontal Fibrosing Alopecia: An Evidence-Based Treatment Update
5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.
![The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression](/images/research/1d65d7d8-24c2-4cc3-816c-a38bd8d67e17/small/20281.jpg)
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer, and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
![5-Alpha-Reductase Inhibitors for Prostate Cancer Chemoprevention: An Updated Cochrane Systematic Review](/images/research/b3fdb55a-72af-4c44-ba23-4909cd3934c4/small/14877.jpg)
research 5-Alpha-Reductase Inhibitors for Prostate Cancer Chemoprevention: An Updated Cochrane Systematic Review
5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
![5-Alpha Reductase Inhibitors: New Evidence on Benefits and Harms Beyond Benign Prostatic Hyperplasia](/images/research/e647c3a1-09a1-4978-92a7-10a556eff1a0/small/13504.jpg)
research 5-Alpha Reductase Inhibitors: New Evidence on Benefits and Harms Beyond Benign Prostatic Hyperplasia
5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
![Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date](/images/research/c47a3f79-d136-49f3-956f-a90699948847/small/4758.jpg)
research Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Finasteride shows promise for female hair loss, but more research needed.
![5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis](/images/research/b319bbc1-b6be-464d-a316-83e9a4258dde/small/18771.jpg)
research 5α-Reductase Inhibitors Alter Steroid Metabolism and May Contribute to Insulin Resistance, Diabetes, Metabolic Syndrome, and Vascular Disease: A Medical Hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
![Treatment Modalities for Lymphocytic and Neutrophilic Scarring Alopecia](/images/research/767e3325-525b-4321-8fea-615695586f2e/small/20110.jpg)
research Treatment Modalities for Lymphocytic and Neutrophilic Scarring Alopecia
Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.
![Effects of 5-Alpha Reductase Inhibitors](/images/research/3c943f9c-e29c-415d-80d6-dd6f2daa778e/small/13658.jpg)
research Effects of 5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
![Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors](/images/research/71666c97-1f9e-4b34-9151-be0a5b9f73b5/small/18128.jpg)
research Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
![Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites](/images/research/87ca3c21-0b49-4fe7-824c-9576c1426899/small/17490.jpg)
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
![Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women](/images/research/36abdfa0-4f6b-40b4-9a45-7680dfe1d1e7/small/3249.jpg)
research Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women
Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.
![Hormone Therapy in Acne](/images/research/405d7689-56d3-40df-b1fc-648dc8ac95ef/small/25957.jpg)
research Hormone Therapy in Acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
![Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss](/images/research/5ce228cb-49b0-4eb6-b16f-42fd1ee0ae84/small/2968.jpg)
research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
![Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia](/images/research/78f56da0-3ff1-41a6-bcf3-92023f238da5/small/18646.jpg)
research Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia
Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
![Targets to Treat Androgen Excess in Polycystic Ovary Syndrome](/images/research/3e157f10-5883-45b8-a7aa-1429698a4bf7/small/14181.jpg)
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
![Safety of 5α-Reductase Inhibitors and Spironolactone in Breast Cancer Patients Receiving Endocrine Therapies](/images/research/67dcb43c-67cb-4d87-8936-967958e613cd/small/17815.jpg)
research Safety of 5α-Reductase Inhibitors and Spironolactone in Breast Cancer Patients Receiving Endocrine Therapies
The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.