research Dutasteride Improves Nocturia but Does Not Lead to Better Sleep: Results from the REDUCE Clinical Trial
Dutasteride can reduce night-time urination but it doesn't improve sleep quality.
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research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research In Silico Structural Prediction of Human Steroid 5α-Reductase Type II
Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
research Cerebral Venous Sinus Thrombosis Associated with Dutasteride Use
Dutasteride for hair loss might increase the risk of a rare stroke type.
research This Week in JAMA: March 7, 2012 Issue Highlights
Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.
research Clinical Pearls in Men's Health
The conclusion is that individualized treatment and proper medication use are crucial in men's health, with specific recommendations for ED, BPH, and prostate cancer management.
research In Vitro 5α-Reductase Inhibition by Selected Ayurvedic Herbs for Androgenic Disorders
Emblica officinalis and Eclipta alba may help treat hair loss naturally.
research Response to Letter Regarding Androgen Receptor PolyQ Alleles and COVID-19
The authors maintain that shorter androgen receptor alleles may lead to milder COVID-19 by positively affecting the immune response, not due to changes in testosterone levels or activity.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Hair Loss in Women: Female Androgenetic Alopecia and Female Pattern Hair Loss
The document concludes that hair loss in women can be treated with topical treatments or hormone therapy depending on the cause.
research Finasteride-Mediated Hair Regrowth and Reversal of Atrophy in a Patient with Frontal Fibrosing Alopecia
Finasteride helps hair regrowth in frontal fibrosing alopecia.
research Role and Mechanisms of Phytochemicals in Hair Growth and Health
Natural products and phytochemicals may help with hair regrowth, but more research is needed.
research Investigations of 13 Genes in Non-Cicatricial Alopecia
DNA analysis can help tailor alopecia treatment.
research The Challenging Role of Antiandrogens in the Management of Polycystic Ovary Syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research No Increased Risk of Cardiovascular Events with Dutasteride vs Finasteride
Dutasteride and finasteride have equal safety for treating BPH without increased heart risk.
research Dutasteride, Finasteride: No Increased Risk of Erectile Dysfunction
Dutasteride and finasteride don't raise erectile dysfunction risk.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Five-Alpha Reductase Inhibitor and Breast Cancer Risk in Men: A Systematic Review
Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
research Hair Loss Treatment Shows Anti-Inflammatory Activity In Vitro
New natural hair loss treatments seem safer but need more research.
research Sexual Dysfunction After 5-Alpha Reductase Inhibitor Use: Insights from the Reduce Study Group Database
Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.
research Most Recent Findings of Curative Drugs for Lower Urinary Tract Symptoms in Clinical Practice
Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.
research Hair Diameter vs. Hair Density in Male Androgenetic Alopecia
Hair loss is due to thinner hairs, not less hairs; hair diameter indicates balding progression and treatment effectiveness.
research 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence
5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
research Sponsored Lecture 3: Updates on 5 Alpha-Reductase Inhibitors (5ARIs) for the Treatment of Male Pattern Hair Loss (MPHL)
5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.
research Current Pharmacological Treatment for Male LUTS Due to BPH: Dutasteride or Finasteride?
Both dutasteride and finasteride improve urinary symptoms, but dutasteride may be better at reducing the risk of prostate surgery and sudden inability to urinate.
research Chronic Administration of a LIMK2 Inhibitor Improves Cavernosal Veno-Occlusive Dysfunction Through Suppression of Cavernosal Fibrosis in a Rat Model of Erectile Dysfunction After Cavernosal Nerve Injury
Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
research Improvement of Androgenetic Alopecia with Combined Low-Dose Dutasteride and Finasteride Therapy: A Case Report
Combining low-dose dutasteride with finasteride improved a man's hair loss.
research Anti-Androgens May Protect Against Severe COVID-19 Outcomes: Results From a Prospective Cohort Study of 77 Hospitalized Men
Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.
research Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review
5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
research A 25-Year-Old Man with Androgenetic Alopecia Developed Symptoms of Post-Finasteride Syndrome After Treatment with Finasteride and Dutasteride
Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.