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Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Melatonin directly affects mouse hair follicles and may influence hair growth.

New nanocarriers improve drug delivery for disease treatment.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Adding a second method to PROTACs could improve cancer treatment.

Piezoelectric Nanogenerators are promising for non-invasive health monitoring but need efficiency and durability improvements.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Coffee bean residue extract helps hair growth by activating cell processes.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Extracts from Alnus sibirica and oregonin may help with hair growth and prevent hair loss.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Sphinganine can reduce hair loss and improve scalp health.

Hemp is a promising ingredient for skin products due to its healing and soothing properties.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.