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Long-term finasteride use doesn't change bone density or metabolism.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Compound 4 is a promising treatment for hair loss with low toxicity.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Treatments for hair loss vary, but cell-based options may be the future.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

Natural products and phytochemicals may help with hair regrowth, but more research is needed.