384 citations
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June 2005 in “Genes & development” This study found that stabilized beta-catenin is crucial for activating stem cell transition from quiescence to proliferation in hair follicles by influencing gene expression within the stem cell niche.
51 citations
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January 2024 in “Nanoscale” This review highlights recent advancements in using nanotechnology to improve the function and delivery of PROTAC drugs, despite existing challenges like low solubility and poor permeability, aiming to enhance their potential in disease treatment.
40 citations
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March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study visualized mitochondrial metabolism in cultured bovine hair follicles and plucked human hairs, finding that ROS and mitochondrial polarization correlate in specific hair follicle regions, particularly near keratin deposition sites.
21 citations
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January 2018 in “PLoS Genetics” This study found that certain keratin gene mutations associated with pachyonychia congenita are linked to altered enamel structure and increased risk of dental caries.
18 citations
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December 2020 in “Frontiers in cell and developmental biology” This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.
13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.
October 2025 in “Dermatology Practical & Conceptual” In this study, researchers in India determined that 37.8% of patients experienced alopecia associated with COVID-19, particularly linked to disease severity, stressing the need for careful patient history review to guide treatment and reassurance.
October 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This research observed that, in domestic cats like Maine Coon and Rex breeds, a "piebald" coat color pattern is likely influenced by the Silver locus, although the specific mutations involved are yet to be published.
August 2025 in “Psychiatry Neurology and Medical Psychology” This study investigated psychosocial adaptation in women with diffuse alopecia, finding that adaptation disorders, particularly related to depression and anxiety, more significantly impacted psychosocial adaptation than the alopecia's origin, highlighting areas for targeted psychological intervention.
January 2025 in “Journal of Case Reports and Scientific Images” In this case report, a 30-year-old woman with scalp demodicosis experienced resolution of itching, hair shedding, and facial lesions after six weeks of topical metronidazole, highlighting the importance of early trichoscopic diagnosis and treatment for Demodex mite infestations.
October 2023 in “Dermatology practical & conceptual” This study observed that among 120 patients recovering from COVID-19, severe diffuse hair loss typically began less than two months post-infection, with the majority of patients experiencing a severe degree of hair loss and positive hair pull tests, often alongside vitamin D deficiency.
January 2023 in “Health Sciences” The authors concluded that while increased androgens in men may link androgenetic alopecia with severe COVID-19, further research on a larger population is needed to verify this association.
January 2008 in “Annals of Nutrition and Metabolism” This study suggests that a specific region upstream of the TGF-β1 gene may play a key role in androgenetic alopecia by regulating gene expression in a cell-specific manner.
2 citations
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July 2015 in “Case Reports in Dermatology” In this case study, DDS treatment for LABD was complicated by hemolytic anemia and alopecia, suggesting the need for careful monitoring of these potential side effects.
April 2024 in “African Journal of Biological Sciences” This case report describes a patient with systemic lupus erythematosus who developed Degos disease and non-scarring alopecia, highlighting dermoscopy's role in diagnosis and treatment prognosis.
December 2018 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive skin procedures, but it reports no new research findings.
7 citations
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March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
1 citations
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March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
10 citations
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February 2022 in “JMIR Dermatology” This systematic review indicates that patients with Down syndrome have an increased prevalence of various dermatologic disorders, especially infectious, inflammatory, autoimmune, and connective tissue conditions.
This review found an increased prevalence of common skin disorders, such as infectious and inflammatory conditions, in patients with Down syndrome and highlighted the need for improved screening and management guidelines.
11 citations
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December 2013 in “Clinical and experimental dermatology” This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.
April 2025 in “Dermatology Practical & Conceptual” This study found that erosive pustular dermatosis of the scalp is frequently misdiagnosed as squamous cell carcinoma, highlighting the need for careful differentiation to avoid unnecessary treatments.
2 citations
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July 2011 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” This study identified genetic variations in the DSG4 gene among sheep, revealing valuable markers for assessing their impact on wool traits.
2 citations
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April 2024 in “Dermatology Practical & Conceptual” This study emphasizes the importance of regular dental check-ups for patients undergoing systemic treatments for psoriatic disease, as it helps prevent oral complications associated with these medications. It recommends collaboration between dermatologists and oral health specialists to effectively manage and communicate these risks.
6 citations
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April 1990 in “The Journal of Dermatologic Surgery and Oncology” Dermatologic surgery has greatly improved with new techniques over the years.
3 citations
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August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
June 2024 in “International Journal of Pharmaceutical Quality Assurance” This study established a new reverse-phase high-performance liquid chromatography method to accurately and precisely quantify silodosin and dutasteride in mixtures, meeting International Council of Harmonization validation criteria for stability, sensitivity, and recovery.
64 citations
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October 2018 in “Thérapie” This report describes the enhancement of the French SNIIRAM/SNDS healthcare database through external data linkages, highlighting its potential use in medical research despite complexities in the integration process.
33 citations
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December 2005 in “British Journal of Clinical Pharmacology” This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.
April 2025 in “Dermatology Practical & Conceptual” This study found that erosive pustular dermatosis of the scalp is often misdiagnosed as squamous cell carcinoma, highlighting the importance of biopsy for accurate diagnosis.