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Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Changes in keratin make hair follicles stiffer.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Iron deficiency may contribute to hair loss.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Kenogen increases with hair loss in women.

S100A3 protein is crucial for hair shaft formation in mice.

Minoxidil helps some bald men, but most lose hair again when stopping.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Androgens may block hair growth signals, targeting this could treat hair loss.

The document suggests using standardized methods to track and measure hair loss in alopecia areata, including patient self-assessment and a 50% improvement in specific scores as a treatment goal.

Rituximab leads to longer remission and fewer side effects than cyclophosphamide.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.