May 2025 in “The Journal of Rheumatology” In this case report, a woman with unexplained hair loss and high ANA levels developed systemic lupus erythematosus, highlighting the importance of monitoring autoantibodies for early lupus detection and management.
April 2023 in “Research Square (Research Square)” This study found that lower GPX4 mRNA levels in polymorphonuclear neutrophils of systemic lupus erythematosus patients were negatively associated with disease activity and serological markers, suggesting a diagnostic value for GPX4 mRNA.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.
February 2021 in “Indonesian Journal of Perinatology” This study found that among 26 pregnant patients with Systemic Lupus Erythematosus, the most common pregnancy complication was intrauterine growth restriction.
January 2020 in “SSRN Electronic Journal” This study observed distinct clusters of autoantibodies in children with pSLE, with significant differences in several clinical manifestations like hair loss, oral ulcers, arthritis, neurological symptoms, renal issues, and AIHA among the clusters.
February 2018 in “Chin J Clinicians(Electronic Edition)” This study found that rash in SLE patients is prevalent and associated with more severe disease indicators, including certain clinical manifestations and serological abnormalities.
This study found that the age of onset in systemic lupus erythematosus patients affects clinical features, with juvenile-onset SLE showing more severe disease activity and systemic involvement than adult or late-onset SLE.
January 2014 in “Journal of Jilin University” This study found that Th22 cells and their cytokine IL-22 may play an important role in the pathogenesis of systemic lupus erythematosus and could serve as bioindicators for monitoring disease severity.
April 2023 in “International Journal of Pharmaceutics” In this study, melatonin-loaded Pickering emulsions stabilized by chitosan-dextran sulphate nanoparticles and enhanced with lecithin showed improved photostability, antioxidant activity, and follicular delivery in androgenic alopecia-affected rats, potentially rivaling commercial minoxidil for hair loss treatment.
January 2022 in “Stem cell biology and regenerative medicine” This review explores the complex interactions between hair follicle stem cells and surrounding structures that are essential for understanding hair regeneration, reporting no new experimental results.
61 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” This review examines beta-catenin's role in stem cell renewal, lineage selection, and tumor formation in the epidermis and reports no new experimental findings.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.
11 citations
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July 2024 in “Cancers” This review discusses common skin toxicities from cancer treatments and offers management strategies, particularly for regions like Australia and New Zealand with high UV exposure.
8 citations
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March 2018 in “Expert Review of Respiratory Medicine” This article reviews the potential of inhalation therapy to restore pulmonary elastin fibers in COPD patients and highlights the need for studies to test its feasibility; it reports no new research findings.
4 citations
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October 2023 in “Fertility and Sterility” This review highlights potential negative impacts of certain medications on male fertility, such as hormonal disruption and germ cell toxicity, emphasizing the importance of clinicians being aware of these effects to advise on safer alternatives.
2 citations
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May 2022 in “Cosmetics” This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.
1 citations
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October 2025 in “Journal of Personalized Medicine” This review discusses various weight loss treatment options for managing PCOS in women, including lifestyle changes, diet, medications, and surgery, but reports no new clinical results.
1 citations
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August 2025 in “International Journal of Molecular Sciences” This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.
May 2024 in “International journal of research in dermatology” This study found that vitamin D deficiency was significantly more prevalent among men with androgenetic alopecia in eastern Uttar Pradesh, India, than in age-matched controls, suggesting a potential link between vitamin D levels and the condition's pathogenesis.
February 2024 in “Medicina-lithuania” This narrative review explores how obesity, related diseases, and bariatric surgery can impact hair health and the hair development cycle, highlighting potential effects such as hair thinning and telogen effluvium.
March 2023 in “Journal of Personalized Medicine” During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.
February 2023 in “Archives of Dermatological Research” This study found fractional carbon dioxide laser therapy effective in treating alopecia areata, both alone and with topical treatments, suggesting decorin's involvement in improving hair growth.
This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.
October 2011 in “Journal of dermatology” A man with a rare skin condition and a new gene mutation developed high calcium levels due to his treatment.
October 2011 in “Dermato-endocrinology” Hormones significantly affect skin health, with vitamin D playing a key role.
November 2020 in “Acta Scientific Women's Health” In this study of women treated for dermatological conditions in West Midlands, England, low vitamin D levels were significantly linked to hair loss, especially in women aged 35-45, suggesting vitamin D's potential role in prevention and treatment of hair loss in this group.
64 citations
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May 2000 in “International Journal of Dermatology” This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.
11 citations
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January 2012 in “Journal of cell science” This study demonstrates that Rac1 activity is essential for normal hair follicle formation but influences hair structure and pigmentation, in terminal differentiation, through alterations in hair shaft, cuticle, and pigmentation organization.
13 citations
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January 2017 in “Molecules” This study reported that compounds isolated from Alpinia zerumbet significantly promoted hair cell growth and exhibited anticancer activity in cell cultures, suggesting potential as treatments for alopecia and cancer.