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Minoxidil 2% effectively treats female hair loss, promoting growth and density.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Minoxidil helps some bald men, but most lose hair again when stopping.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

People with early onset baldness have higher bad cholesterol and lower good cholesterol, increasing their heart disease risk.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

BMP6 and Wnt10b control whether hair follicles are resting or growing.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Minoxidil can cause dangerous fluid buildup around the heart.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.