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This review discusses the research supporting the approval and use of minoxidil for androgenic alopecia and reports no new clinical results, emphasizing recent findings and developments.

In this study, researchers observed that different ERK signal activation dynamics during hair follicle regeneration are linked to cell fate specification and are affected by distinct upstream signaling pathways.

This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.

This review discusses various methods to assess bioequivalence between dermatologic drugs and highlights the potential of visual inspection and percutaneous penetration research.

This review outlines the various adverse reactions to biologic therapies in Allergy/Immunology, emphasizing the clinical and management challenges due to overlapping reaction phenotypes and the need for more refined diagnostic and management strategies.

This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.

In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.

In this case report, a three-generation family with Gorlin-Goltz syndrome showed a heterozygous PTCH1 splice-donor variant associated with the disease, and two affected relatives benefited from individualized, side-effect-guided dosing of the drug sonidegib, experiencing regression of basal cell carcinoma lesions.

In this study, researchers developed a mucoadhesive hydrogel ovule containing retinyl palmitate and curcumin for intravaginal use, showing controlled drug release, selectivity against cancerous HeLa cells, and non-toxicity to healthy cells, which may offer a potential treatment for cervical cancer.

A hair test can accurately predict if a person with hair loss will respond to minoxidil treatment.

This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.

This chapter reviews nanocarriers for acne therapy, highlighting their ability to reduce lesions and inflammation while improving the safety and effectiveness of treatment, though no new clinical results are reported.

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

This study suggests that a nanostructured lipid carrier formulation delivering minoxidil and latanoprost may enhance effectiveness and tolerability in treating alopecia by targeting hair follicles.

This review discusses methotrexate's use in dermatology and its mechanisms, pharmacokinetics, dosing, side effects, interactions, and emphasizes the need for further research into optimizing therapy and predicting adverse events.

This study suggests that a nanostructured lipid carrier formulation of minoxidil and latanoprost may effectively target hair follicles and enhance drug penetration for alopecia treatment.

This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.

This case report suggests that Malarone® may cause acute pancreatitis and alopecia in dogs, highlighting the need for careful monitoring of adverse reactions when using this drug in canine treatment.

Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.

This correspondence reported significant variability between quantitative PCR and bDNA assays for measuring Hepatitis C virus RNA in high-titer specimens, challenging the reliability of the Chiron assay.

This article discusses the use of histoculture in cancer treatment, hair growth studies, and immune response research, but reports no new clinical results.

This study found that bis-benzylisoquinoline and Amaryllidaceae alkaloids, especially aromoline, show potential as antiviral agents, suggesting they could serve as foundations for developing new treatments against coronaviruses by enhancing the understanding of their structure-activity relationships.

In this randomized controlled clinical study, researchers found that Neem and Zanjabeel treatment was as effective as standard hormonal therapy in reducing hirsutism and improving biochemical and hormonal parameters in women with polycystic ovarian disease, while also significantly lowering fasting insulin and lipid levels.

This study developed an efficient LC-MS bioanalytical method to simultaneously quantify minoxidil sulphate and latanoprost in skin layers, supporting the formulation of topical treatments for androgenic alopecia.

This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.

This study found that folic acid-conjugated magnetic nanoparticles loaded with doxorubicin significantly reduced cell proliferation in HeLa cells, although they were not effective against doxorubicin-resistant HeLa cells.

Finasteride caused blisters on hands and feet.

This review covers drug repurposing patent applications from April to June 2021, detailing potential new therapeutic uses for existing medications, but reports no new clinical results; the authors highlight novel treatment possibilities and suggest further research.

In this study using fertilized chicken eggs, researchers reported that ethanol and aqueous extracts of clove, cinnamon, and coriander significantly reduced blood vessel formation, indicating these herbs' potential as safe anti-angiogenic treatments without severe side effects compared to synthetic drugs.

This review highlights novel drug delivery systems for alopecia that enhance localization in the pilosebaceous unit, reduce systemic exposure, and support sustained drug release, with a focus on optimized follicular carriers ranging from 100-300 nm for improved drug residence compared to conventional methods.