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This study highlights the challenges in treating Microsporum canis infections due to variable antifungal drug efficacy and potential resistance, emphasizing the need for standardized methods to assess drug susceptibility.

This study investigated a gelatin-based bioink for 3D bioprinting a simplified skin model, finding that a formulation with 15% gelatin and 150 mM calcium chloride supported a homogeneous distribution of viable cells over 14 days, showing promise for drug evaluation applications.

This study validated an HPLC analytical method for evaluating fenasteride in commercial products, finding it to be sensitive, selective, and within acceptance criteria for specificity, precision, and stability, making it suitable for quality control testing.

This study developed a 3D engineered hair follicle model that mimics the native hair bulb and may aid in drug screening for hair growth therapies.

This study evaluated green tea extract-loaded spanlastic formulations and found that a vesicle builder to edge activator ratio of 8:2 produced optimal characteristics, including a particle size of 419.70 nm, an entrapment efficiency of 60.85%, and a drug loading of 11.07%.

This study determined that the optimal formulation for caffeine-based hydrogels involves 0.2% caffeine and 2.3% chitosan, based on gel liberation and stability testing.

This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.

This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.

This review explores advancements in bioprinting technologies for developing in vitro skin models that replicate immune-mediated skin diseases, highlighting their potential to reduce animal testing and enhance research and product testing capabilities in dermatology.

This review examines experimental and clinical evidence on PDRN, a drug derived from salmon DNA that acts via the adenosine A2A receptor and shows promise for tissue repair and treatment of diabetic foot ulcers in regenerative medicine.

This review highlights the potential of several medicinal plants as treatments for seborrhea dermatitis by inhibiting Malassezia growth and reducing symptoms like itching and redness, amid challenges of drug adherence and side effects in existing therapies.

This review summarizes existing and new cases of generalized pustular psoriasis and acute generalized exanthematous pustulosis associated with COVID-19, noting that over half lacked a known drug trigger.

In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.

This study found that modulating epithelial and mesenchymal cell interactions in vitro enabled nearly 100% efficient induction of hair follicles, suggesting potential applications for understanding and testing hair growth and graying.

In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.

In this study, DanEra, an herbal hair tonic from Pomegranate and Beetroot extracts, showed equivalent effectiveness to the standard drug Ketoconazole in microbiological tests and provided significant relief from severe dandruff in all volunteers within 10 days.

This study found that patients taking hydroxychloroquine had a significantly higher likelihood of indeterminate QuantiFERON-TB Gold test results compared to those not on the medication, independent of other immunosuppressive drug use.

This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.

This study found that 66% of apparently healthy volunteers had some abnormality on biochemical, hematological, or electrocardiographic testing, highlighting the need for pretreatment evaluations in clinical trials.

This study found that finasteride significantly alters urinary steroid profiles, complicating the detection of steroid abuse in doping-control analysis by potentially causing false-negative results.

This study developed microfluidics-based 3D microtumors to model minimal residual disease in ovarian cancer, highlighting their alignment with patient-derived MRD and response to a fatty acid oxidation inhibitor.

This study reports that a novel Nano-Structured Lipid Carrier system for delivering dutasteride may enhance its anticancer effects while reducing systemic side effects in clinical settings.

This study found that several newly synthesized dihydrobenzopyran compounds inhibited insulin secretion and had vasorelaxant activity, with some more potent than reference KATP channel activators, though compound 21 functioned as a Ca2+ entry blocker.

In vitro skin models are improving but still need more innovation to fully replicate human skin.

This review discusses recent advancements made in using mouse models to investigate the genetic complexity and pathogenesis of alopecia areata, emphasizing potential new treatment targets, but it reports no new findings.

This review from JAAD Reviews provides a comprehensive overview of hypertrichosis, discussing its diagnosis, treatment options like topical and laser therapies, and special psychosocial considerations for pediatric patients to better support clinicians and researchers in managing this condition.

This article discusses the use of histoculture in cancer treatment, hair growth studies, and immune response research, but reports no new clinical results.

This study found that while no predictive factors for response to vismodegib were identified, longer treatment duration was associated with a lower risk of relapse in basal cell carcinoma patients.

In this case report from People's College of Medical Sciences, a 20-year-old man initially misdiagnosed with Addison's disease was ultimately found to have strongyloidiasis, with his symptoms and weight loss improving after antihelminthic treatment.

This study reports that activating the bitter taste receptor TAS2R4 with rebaudioside A can inhibit hair growth in human scalp hair follicles by promoting catagen through TGF-β pathway activation.