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The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The document reviews key historical figures and discoveries in dermatology.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Finasteride for hair loss lowers PSA levels, so PSA values need adjusting when screening for prostate cancer.

Minoxidil effectively lowers blood pressure in patients with resistant hypertension.

Dutasteride may lower the chance of finding prostate cancer in men with enlarged prostates.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.