research Identification of Drug-Disease Associations Using Information of Molecular Structures and Clinical Symptoms via Deep Convolutional Neural Network
A new model can predict drug-disease links well, helping drug research.
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research Lessons Learned from the First Decade of Laser-Assisted Drug Delivery
Laser-assisted drug delivery has shown improved treatment outcomes for skin conditions and has potential to reduce side effects and treatment time.
research Comprehension Testing for Over-the-Counter Drug Labels: Goals, Methods, Target Population, and Testing Environment
The paper concludes that drug labels should be clear for all, especially for those with low literacy, and suggests aiming for high comprehension test passing rates with diverse test populations.
research Spontaneous Cutaneous Adverse Drug Reaction Reports: An Analysis of a 10-Year Dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System That Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice
A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Laser-Assisted Drug Delivery for the Treatment of Androgenetic Alopecia: Ablative Laser Fractional Photothermolysis to Enhance Cutaneous Topical Delivery of Platelet-Rich Plasma — With or Without Concurrent Bimatoprost and/or Minoxidil
Laser-assisted delivery of PRP, with or without bimatoprost and minoxidil, can effectively stimulate hair growth.
research Bendamustine: An Old Drug in the New Era for Patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.
research Bicalutamide: A Potential New Oral Antiandrogenic Drug for Female Pattern Hair Loss
Bicalutamide may be a promising alternative treatment for female pattern hair loss.
research Association Between Gender and Drug Cost for Over-the-Counter Minoxidil
Women pay more for the same 5% minoxidil foam than men, but prices for liquid solutions are similar.
research The Role of Aquaporins in Polycystic Ovary Syndrome: A Way Towards a Novel Drug Target in PCOS
Aquaporins could be new drug targets for treating polycystic ovary syndrome.
research Suspected Cutaneous Drug Toxicity in Rheumatoid Arthritis—An Evaluation
Most skin rashes in rheumatoid arthritis patients were not caused by their medication, and careful evaluation allowed most to keep taking their beneficial treatment.
research Patents on Nanoparticulate Drug Delivery Systems: A Review
The document reviews patents on nanoparticle systems used to deliver drugs, discussing their creation, use in treatments, and commercial applications.
research Novel Causes of Drug-Induced Occupational Asthma
Four new substances—minoxidil, ferrimanitol ovalbumin, clarithromycin, and glucosamine-hydrochloride—can cause occupational asthma.
research Niosomes: A Novel Targeted Drug Delivery System
Niosomes are a promising method for delivering drugs directly to targeted areas in the body.
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research DNN-DTIs: Improved Drug-Target Interactions Prediction Using XGBoost Feature Selection and Deep Neural Network
The DNN-DTIs method accurately predicts drug-target interactions and is useful for drug repositioning.
research The Pattern of Off-Label and Unlicensed Drug Use in Adult and Pediatric Patients in the Kingdom of Saudi Arabia: Multicenter Retrospective Study
Most off-label drug prescriptions in Saudi Arabia are for adults with depression and diabetes.
research Entrepreneurship in Off-Label Drug Prescription: Just What the Doctor Ordered!
The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
research Finasteride: A New Drug for the Treatment of Male Hirsutism and Androgenetic Alopecia?
research Alopecia and Drug Eruption of the Scalp Associated with a New Beta-Blocker, Nadolol
Stopping the beta-blocker nadolol led to quick hair regrowth and improved scalp condition.
research Hair Loss After Drug Reaction With Eosinophilia and Systemic Symptoms: A Multicentric Retrospective Case Series
Some types of hair loss can continue for a long time after recovering from a severe drug reaction known as DRESS.
research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases
Finasteride may be linked to Peyronie’s disease, but more research is needed.
research An Urticarial Drug Eruption Caused by Tofacitinib for Alopecia Universalis
A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
research An In Situ Chemotherapy Drug Combined with Immune Checkpoint Inhibitor for Chemoimmunotherapy
Combining specific nanoparticles with immune therapy significantly improves cancer treatment.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Use of the Drug Wolvit (Biotin 5 mg) in Treatment of Diffuse Telogen Alopecia
Wolvit® (biotin 5 mg) is effective and safe for treating hair loss and scalp conditions in women.
research Ixekizumab Improves Physical Function, Quality of Life, and Work Productivity in Biologic Disease-Modifying Antirheumatic Drug-Naive Patients with Active Psoriatic Arthritis
Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.
research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.