research Probable Drug-Triggered Pemphigus Foliaceus in a Dog Following Administration of Afoxolaner (NexGard)
A dog developed a skin condition called pemphigus foliaceus after taking NexGard, but got better with treatment.
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research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.
research Drug News
The FDA approved a new breast cancer treatment, found flu shots may reduce heart risks, questioned the safety of fast-tracked drug approvals, showed statins don't help with certain pneumonia, and approved a new dementia imaging agent.
research Designing, Optimizing, and Assessing a Novel Emulgel Containing Minoxidil for Controlled Drug Release Using Marine-Based Polymers
The new minoxidil emulgel with marine-based polymers shows effective controlled drug release for hair growth treatment.
research Psoriasiform Drug Eruption to Finasteride: Uncommon Side Effect of a Commonly Used Drug
Finasteride can cause rare but serious skin rashes.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research The Role of Aquaporins in Polycystic Ovary Syndrome: A Way Towards a Novel Drug Target in PCOS
Aquaporins could be new drug targets for treating polycystic ovary syndrome.
research Novel Causes of Drug-Induced Occupational Asthma
Four new substances—minoxidil, ferrimanitol ovalbumin, clarithromycin, and glucosamine-hydrochloride—can cause occupational asthma.
research Entrepreneurship in Off-Label Drug Prescription: Just What the Doctor Ordered!
The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
research Alopecia and Drug Eruption of the Scalp Associated with a New Beta-Blocker, Nadolol
Stopping the beta-blocker nadolol led to quick hair regrowth and improved scalp condition.
research Rare Combination of Adverse Effects Associated With Lamotrigine Treatment
A young man had rare serious side effects from an epilepsy drug, leading to stopping the drug.
research Cutaneous Adverse Drug Reaction Associated With Topical Use of Benzyl Benzoate in a Dog
Improper use of benzyl benzoate on a dog can cause severe skin reactions.
research Ketoconazole: A Promising Drug for Fungal Infections
Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.
research Editorial: Retinoids — Dermatologists’ Drug of the Decade
Retinoids are important for treating skin conditions but should be used with caution due to serious side effects and risks during pregnancy.
research Albendazole Treatment of Echinococcosis in Humans: Effects on Microsomal Metabolism and Drug Tolerance
Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.
research ER71/ETV2 Promotes Hair Regeneration from Chemotherapy-Induced Hair Loss by Enhancing Angiogenesis
The protein ER71/ETV2 helps regrow hair after chemotherapy by improving the growth of new blood vessels.
research FDA Declines Approval of Testosterone Drug for Third Time
The FDA rejected a testosterone drug again due to safety concerns.
research A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Synthesis and Characterization of Inclusion Complex of the Vasodilator Drug Minoxidil with β-Cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research A Top-Down Design Approach for Generating a Peptide PROTAC Drug Targeting Androgen Receptor for Androgenetic Alopecia Therapy
A new AI-driven method shows promise for treating hair loss with a peptide-based drug.
research Two Cases of Stroke Associated with the Use of Finasteride, an Approved Drug for Male-Pattern Hair Loss in Japan
Finasteride, a hair loss medication, may be linked to stroke in young men.
research Nosocomial Intravascular Catheter Infections with Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli in Calves After Strain Introduction from a Commercial Herd
A hospital outbreak of catheter infections in calves was caused by a bacteria from a beef herd, leading to longer hospital stays, more drug use, and calf deaths.
research Hair Loss Diagnosis and Treatment Knowledge-Based System
Hair loss causes emotional distress, leading to high spending on treatments, with Minoxidil and Propecia being common but having side effects.
research Cyberspace Chat: When Finasteride Suddenly Stops Working—Is It Counterfeit?
Some generic finasteride may be counterfeit, leading to less effectiveness and increased hair loss.
research Follicular Transport Route: Research Progress and Future Perspectives
Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
research The Prescribing Cascade 3.0: A Case for Recreational Drugs in HIV
Recreational drug use can cause misdiagnosed conditions and drug interactions in HIV patients.
research Cell-Cell Interaction in the Hair Follicle Niche in Androgenetic Alopecia
New drug targets for hair loss treatment were identified by studying cell interactions in hair follicles.
research Cetuximab-Induced Hypertrichosis of the Scalp and Eyelashes
A cancer drug caused unusual hair growth on a 100-year-old man's scalp and eyelashes.
research Eosinophilic Pleuropericardial Effusion Due to Valproic Acid
Valproic acid can cause a rare allergic reaction leading to fluid around the lungs and heart, which is treatable by changing medication.