Search

everythinglearnresearchcommunity

for

Search:↓

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.

Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

Adopting the Mark Cuban Cost Plus Drug Company pricing model could save Medicare about $1.29 billion on urological drugs.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

Infrared light can trigger drug release from gold nanoparticle carriers in hair follicles.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Hair lipids do not protect against humidity.

Sunlight exposure increases drug toxicity; amber glass best for protection.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Imatinib can cause hair loss due to lichen planopilaris.

Created finasteride complex to increase water solubility and drug release.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.

Certain drugs, especially those for eyes, bacterial infections, imaging tests, and skin conditions, are more likely to cause itching, with differences seen across gender, age, and weight.

Cialis and Finasteride could be repurposed to treat aggressive melanoma.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

A blood pressure drug, diltiazem, may also help treat influenza.

Some patients lost hair after being treated with the drug enoxaparin for a brain vein clot.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.