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Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

The document reviews key historical figures and discoveries in dermatology.

A new protein linked to Alzheimer's was discovered, and a hair loss treatment showed effectiveness but had some sexual side effects.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Polyamines help fix DNA damage accurately in cells.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Dutasteride is more efficient than finasteride, but individual results vary.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.

Monitoring new epilepsy drugs after they're sold is crucial to find rare and long-term side effects that initial tests might miss.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.

Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.

Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.

The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.