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Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Tofacitinib might be used to treat hair loss.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

α-mangostin nanoparticles improved acne with minimal irritation.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.

Ethosomal carriers effectively deliver hair loss drug into skin.

Using electronic health records can help identify drug side effects but has some limitations.

Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Drug repurposing shows promise for treating many medical conditions.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

A blood pressure drug, diltiazem, may also help treat influenza.

Some patients lost hair after being treated with the drug enoxaparin for a brain vein clot.

New method makes important drug ingredients more easily without needing extra purification steps.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.