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187 citations,
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July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
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Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
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The hydrogel with 20% Hibiscus rosa-sinensis extract was the best for potential therapeutic use.