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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

PLD is an effective and safer alternative for treating breast cancer.

Activating TRPV3 stops human hair growth.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Skin fat helps with body temperature control and has other active roles in health.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.