147 citations,
January 2003 in “American journal of clinical dermatology” The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
125 citations,
August 2020 in “Frontiers in Immunology” Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
119 citations,
November 2009 in “Human Reproduction” Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
116 citations,
April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
106 citations,
April 2013 in “Dermatologic Surgery” Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.
106 citations,
June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
105 citations,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
101 citations,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
97 citations,
September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
88 citations,
December 2018 in “Advanced Healthcare Materials” Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
86 citations,
July 2012 in “British journal of dermatology/British journal of dermatology, Supplement” There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.
76 citations,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
75 citations,
January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
74 citations,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
68 citations,
March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
60 citations,
February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
60 citations,
January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
59 citations,
October 2012 in “Pharmaceutical Research” Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.
58 citations,
November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
56 citations,
January 2001 in “Dermatology” Teloptosis is a key point in hair loss that could help in creating prevention-focused hair care strategies.
55 citations,
June 2009 in “Journal of Pharmaceutical Sciences” Minoxidil promotes hair growth by penetrating skin, with ethanol-containing formulas working best.
55 citations,
June 2007 in “Journal of Statistical Planning and Inference” The flexible fixed-sequence testing method allows for more effective evaluation of multiple goals in a clinical trial while controlling the risk of false positives.
53 citations,
May 1987 in “The Lancet” The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.
52 citations,
September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
52 citations,
January 2001 in “Eye” Treating cystoid macular oedema in uveitis is difficult and risky.
50 citations,
February 2018 in “Biomedicine & pharmacotherapy” Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.