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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Skin fat helps with body temperature control and has other active roles in health.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Traditional and complementary medicine may help with skin conditions, but more high-quality research is needed.

Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.