1 citations
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September 2025 in “Frontiers in Immunology” In this study, researchers using a Treg-specific HuR-deficient mouse model found that the RNA-binding protein HuR is crucial for stabilizing Foxp3 mRNA, affecting Treg function and immune regulation, with HuR disruption leading to impaired Foxp3 expression and potential autoimmune dysfunction.
353 citations
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May 2016 in “TrAC Trends in Analytical Chemistry” This review discusses recent advances in droplet microfluidics for chip-based technologies such as single-cell analysis, small-scale cell cultures, and high-throughput drug screening, and it reports no new results.
February 2026 in “Apollo (University of Cambridge)” This review highlights the use of droplet microfluidics in microgel fabrication, emphasizing its ability to control microgel properties and discussing applications in areas like drug delivery and tissue engineering, as well as addressing current challenges and future research directions.
71 citations
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October 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study highlights the complex role of the vitamin D receptor in skin processes, where its disruption, along with calcium and co-regulator imbalances, could contribute to skin cancer development by altering skin differentiation and hair follicle cycling.
January 2020 in “Journal of the Brazilian Chemical Society” This study suggests that using nanostructured lipid carriers may improve the targeting of 17-α-estradiol in treating alopecia by improving skin penetration and stability.
3 citations
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June 2023 in “Advanced Materials” This study reported that a self-pumping organohydrogel dressing equipped with hydrophilic fractal microchannels significantly increased exudate drainage efficiency and enhanced burn wound healing in mice, reducing dermal cavity size and accelerating blood vessel and hair follicle regeneration compared to commercial dressings.
5 citations
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August 2023 in “Preprints.org” This review outlines recent advancements in droplet-based microfluidics used with food-grade materials to create delivery systems, emphasizing the design and function of systems like emulsions and microcapsules while discussing challenges related to scaling these processes from lab to industry.
2 citations
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December 1954 in “Experimental Biology and Medicine” This study found that fluid loss through rat skin increases with heightened skin activity and hair growth, while linoleic acid penetration during inactive conditions enhances water loss.
78 citations
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November 2005 in “Endocrinology” This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.
76 citations
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January 2010 in “Journal of bone and mineral metabolism” 50 citations
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September 2009 in “Molecular Genetics and Metabolism” This study identified a novel V26M mutation in the vitamin D receptor as the cause of hereditary vitamin D resistant rickets in a patient, characterized by severe rickets and an unusual pattern of alopecia.
41 citations
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that deleting the MED1 subunit from the MED complex in keratinocytes resulted in disrupted hair differentiation and cycling, leading to hair loss in mice.
37 citations
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October 2006 in “Archives of Biochemistry and Biophysics” This study describes a patient with hereditary vitamin D resistant rickets (HVDRR) who, despite having a truncated vitamin D receptor, did not exhibit typical hair or skin abnormalities, suggesting possible compensation via interactions with other proteins.
15 citations
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January 2015 in “Skin Appendage Disorders” This report discusses a series of patients with frontal fibrosing alopecia experiencing increased scalp sweating, which the authors hypothesize may be related to local skin inflammation affecting sweat gland activity.
5 citations
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March 2012 in “Journal of Investigative Dermatology” In their mouse study, Oda et al. found that removing the MED1 gene in the skin led to hair loss and changes in epidermal cell differentiation, indicating MED1's significant role in these processes.
4 citations
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January 2009 in “International journal of trichology” Minoxidil topical foam is a better, less irritating treatment for hair loss.
2 citations
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December 2019 in “Chinese medical journal/Chinese Medical Journal” This case report describes a rare instance of tinea capitis caused by Trichophyton tonsurans in a Chinese patient, followed by the development of herpes zoster, suggesting a potential link to immunosuppression.
1 citations
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January 2019 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a gel containing extracts from Coffea arabica and Larrea divaricata was found to significantly thicken eyebrows and eyelashes in most premenopausal and postmenopausal women, without causing adverse effects, but showed no statistical difference from a placebo in overall hair growth.
June 2026 in “Journal of Comprehensive Dermatology” This study reviewed the evidence on minoxidil's effectiveness for androgenetic alopecia, finding that 5% topical minoxidil is the most effective monotherapy for men, while 2% is similarly effective for women. Genetic markers can predict response, and new formulations like foam and gel improve tolerability.
January 2026 in “International Journal of Biological Macromolecules” The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.
April 2014 in “Emergency Medicine News” This case report highlights the diagnostic challenges of thyroid storm, emphasizing the importance of a thorough history and review of systems to differentiate it from other conditions.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal nanoemulgel-based hair dyes, incorporating natural ingredients, enhance dye penetration and retention while providing additional hair and scalp health benefits compared to conventional dyes, though further studies are needed to confirm long-term safety and efficacy.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that herbal nanoemulgel-based hair dyes, enriched with natural ingredients, improve dye penetration and retention and offer additional hair and scalp benefits compared to conventional dyes, although further research is necessary to verify their safety and efficacy for long-term use.
This study developed a novel protocol that demonstrated improved localized delivery of minoxidil to eyebrow application sites with minimal runoff, compared to a control formulation.
14 citations
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September 2023 in “Foods” This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.
5 citations
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February 2017 in “Cochrane library” This review discusses various topical medication instillation techniques for managing glaucoma but reports a lack of evidence on their effectiveness compared to usual care.
August 1994 in “Journal of Dermatological Science” 15 citations
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April 2023 in “Biology” This review discusses the characteristics, extraction strategies, and potential applications of plant and algal lipid droplets but reports no new empirical findings.
This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.
378 citations
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February 2020 in “Nature Reviews Endocrinology”