January 2025 in “International Journal of Veterinary Science” In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.
April 2026 in “International Journal of Drug Delivery Technology” The study developed herbal shampoo formulations using isolated phytoconstituents, such as eugenol, rutin, menthol, and camphor, which demonstrated similar antifungal efficacy to ketoconazole but with improved safety and detergency, offering a promising alternative for managing seborrheic dermatitis.
32 citations
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April 2016 in “Aaps Pharmscitech” This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.
February 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this review, researchers explored the potential of herbal shampoos as effective and safe alternatives to conventional anti-dandruff treatments, highlighting that polyherbal formulations may offer comparable or superior benefits with fewer side effects.
March 2005 in “Journal of The American Academy of Dermatology” Herbal extract improves hair growth in female pattern baldness.
57 citations
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September 2017 in “Journal of controlled release” This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.
5 citations
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August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
1 citations
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November 2024 in “Pharmaceutical Sciences” This review study found that vesicular carriers like liposomes, niosomes, invasomes, and transferosomes can enhance drug penetration through follicles, benefiting treatments for alopecia, acne, and infections, as well as potentially facilitating systemic delivery of antihypertensive drugs and insulin.
55 citations
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August 2015 in “AAPS PharmSciTech” This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.
13 citations
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October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
12 citations
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March 2020 in “Journal of Bioactive and Compatible Polymers” This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
4 citations
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January 2022 in “Current pharmaceutical design” This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
This study analyzes the application of a new hair serum incorporating natural ingredients like Aloe vera and ginger, finding it potentially beneficial for managing hair frizz, improving smoothness, and preventing damage without significant adverse reactions.
January 2024 in “International Journal of Clinical Pharmacokinetics and Medical Sciences” The researchers in this study suggest that using plant-based hair serums, which combine herbs and botanical phytochemicals, can enhance therapeutic benefits for hair and skin, offering improvements like deep nutrition, skin suppleness, and UV protection compared to individual herb use.
35 citations
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April 2006 in “Ocular Surface” This review discusses adverse effects of cosmetic products and procedures on the ocular surface, including mild discomfort to severe vision-threatening conditions, and reports no new clinical results.
9 citations
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July 2017 in “Journal of Drug Delivery Science and Technology” This study suggests that a microemulsion formulation of Minoxidil effectively enhances drug delivery through hair follicles, showing significant follicular response alterations in an alopecia model.
34 citations
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September 1992 in “Journal of the American Academy of Dermatology” This article provides dermatology residents with essential information on cosmetic use to help manage skin conditions and reactions, without reporting new clinical results.
20 citations
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July 1988 in “Clinics in dermatology” This article reviews the current practices and interpretations of research data on permanent waving and hair straightening, but does not present any new research findings.
9 citations
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January 2010 This study reports that a 100% herbal hair dye composed primarily of Cymphomandra betacea, Tagetes erecta, and Aloe vera gel provides permanent hair color without causing hair damage, loss, or skin irritation compared to synthetic dyes.
4 citations
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January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
1 citations
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December 2021 in “Annals of phytomedicine” This study found that a herbal hair dye formulated with a 1:2 ratio of henna and indigo successfully colored unpigmented hair dark brown to black, with favorable attributes compared to synthetic dyes.
1 citations
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March 1954 in “Archives of dermatology” This article reviews small animal experiments reported from 1932 to 1952 in two dermatology journals and notes the contributions of Farris's book on laboratory animal care.
15 citations
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July 2015 in “Journal of Essential Oil Bearing Plants” This review discusses the phytoconstituents and biological properties of T. orientalis and T. occidentalis, but reports no new clinical results.
1 citations
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October 2025 in “Frontiers in Immunology” In this study, researchers analyzed adverse events linked to avacopan using FDA data, finding no high-priority safety concerns but identifying five potential new adverse events, including alopecia, primarily among American patients, and noting a higher risk of liver dysfunction in Japanese patients.
January 2026 in “Frontiers in Immunology” This case study details a 44-year-old woman with rheumatoid arthritis and systemic lupus erythematosus who developed hypereosinophilic asthma and was initially treated as ANCA-negative eosinophilic granulomatosis with polyangiitis. Her condition, eventually classified as HASM, underscores the need for evaluating EGPA-spectrum disorders in similar scenarios.
February 2023 in “International Journal of Pharmaceutics” In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.
February 2014 in “PubMed” This study found that Lycopersicon esculentum extracts applied to mice promoted hair growth similarly to minoxidil and increased growth factor expression, suggesting potential in hair loss treatments without skin irritation.
3 citations
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August 2021 in “The Open Dermatology Journal” This study found that the formulated herbal hair serum improved hair growth and hair weight with minor sensitivity after application and demonstrated stability for seven days.
96 citations
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September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
25 citations
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February 2024 in “Pharmaceutics” This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.