September 2024 in “Genes” This study found that overexpressing CRABP1 in dermal papilla cells promotes their proliferation and influences key genes in the Wnt/β-catenin signaling pathway, which may offer insights into mechanisms controlling hair follicle development.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
January 2024 in “Aesthetic Plastic Surgery” This study found that botulinum toxin type A inhibited apoptosis in dermal papillary cells induced by dihydrotestosterone through the circ_0135062/miR-506-3p/Bax axis.
November 2022 in “Journal of Investigative Dermatology” This study found that non-balding dermal papilla cells emphasized extracellular matrix organization and reduced inflammation when cultured in 3D or with adipose-derived stem cells, unlike balding cells which maintained inflammatory pathways.
April 2022 in “Research Square (Research Square)” This study established the R-7 dermal papilla cell line, which retained essential characteristics of primary cells without undergoing malignant transformation, suggesting its potential for future hair research.
April 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that adipose-derived stem cell exosomes increased dermal papilla cell proliferation and elevated proteins linked to hair follicle inducibility in vitro.
This study found that ocu-miR-205 promotes the apoptosis of dermal papilla cells and the transformation of hair follicles from growth to regression and resting phases in Rex rabbits.
This study found that ocu-miR-205 influences hair follicle density in Rex rabbits by promoting dermal papilla cell apoptosis and transforming hair follicles from growth to resting phases through signaling pathway modulation.
June 2019 in “PRISM (University of Calgary)” This research reported that dermal progenitor cells can enhance split-thickness skin graft outcomes by improving dermal layer qualities and reducing itch and offer potential in skin wound healing using a flowable hydrogel for better cell delivery and survival.
January 2019 in “Proceedings for Annual Meeting of The Japanese Pharmacological Society” In this study, injecting Nε-(carboxymethyl) lysine into skin tissue weakened hair shaft and follicle formation, likely by inhibiting cell proliferation and migration needed for hair follicle morphogenesis.
September 2017 in “Journal of Investigative Dermatology” This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.
April 2017 in “Journal of Investigative Dermatology” This study found that lymphatic vessels promote hair follicle growth in mice, suggesting new therapeutic strategies for hair loss treatments.
March 2014 in “Journal of The American Academy of Dermatology” Azathioprine may help with severe hair loss, a new topical treatment could counteract hair thinning, and trichoscopy can diagnose hair-pulling disorder effectively.
March 2014 in “Journal of The American Academy of Dermatology” Cortexolone 17a-propionate may be an effective new treatment for hair loss.
This study found that Clitocybin A from Clitocybe aurantiaca may promote hair growth in immortalized rat dermal papilla cells by enhancing cell proliferation and activating Wnt/β-catenin signaling and ERK pathways.
In this study, the n-hexane fraction of wheat bran significantly promoted hair growth in rat vibrissa follicles and triggered the telogen-anagen transition in C57BL/6 mice, likely through cell cycle and Wnt/β-catenin signaling pathways.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
21 citations
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April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.
2 citations
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April 2024 in “Dermatology Practical & Conceptual” This study found that Janus Kinase inhibitors, tofacitinib and baricitinib, showed effectiveness and safety in treating severe alopecia areata in a real-world setting, with optimal tolerability noted in younger individuals.
1 citations
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April 2025 in “Dermatology Practical & Conceptual” In this study, trichoscopy was highlighted as a valuable diagnostic tool for traction alopecia, particularly in black women, revealing common signs like vellus hair and hair casts, although it requires a suggestive clinical history for effective use.
January 2026 in “Dermatology Practical & Conceptual” This study suggests that side effects of low-dose oral minoxidil for hair loss are infrequent and demographics did not influence this risk, but dosage relative to body weight may affect adverse event incidence.
7 citations
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October 2018 in “Dermatology practical & conceptual” This study found that topical oxygen therapy may be a beneficial adjuvant treatment for hair loss, acne, and chronic dermatological conditions, though further research is needed to confirm its effectiveness.
3 citations
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January 2023 in “Dermatology Practical & Conceptual” In this study, the researchers reported that ischemia-modified albumin and IMA/albumin levels may not effectively predict disease severity in patients with alopecia areata.
2 citations
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January 2023 in “Dermatology Practical & Conceptual” This study found that patients with alopecia areata had a higher frequency of the AB+ blood group compared to healthy controls.
1 citations
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July 2022 in “Dermatology practical & conceptual” Square-shaped hair loss can occur after treating a brain aneurysm due to localized radiation exposure.
October 2022 in “Dermatology practical & conceptual” This study found that bipolar disorder is more prevalent in patients with hidradenitis suppurativa than in those with psoriasis or in control groups.
October 2021 in “Dermatology practical & conceptual” A Saudi girl was diagnosed with Loose Anagen Hair Syndrome, a rare condition causing easy hair loss without scarring.
19 citations
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October 2019 in “Dermatology Practical & Conceptual” This review discusses the expanding applications of dermoscopy in dermatological diagnosis beyond its initial use for detecting dysplastic nevi and reports no new clinical results.
10 citations
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October 2024 in “Dermatology Practical & Conceptual” This study found that dupilumab's effects on alopecia areata varied depending on patients' immune profiles, with Th2-skewed females seeing improvements and Th1-driven males experiencing worsening.