July 2019 in “Dermatology practical & conceptual” This report presents personal observations of alopecia areata in twins with autoimmune thyroiditis and suggests a possible link, though it does not provide new clinical results.
October 2022 in “Dermatology practical & conceptual” This study found that micro-needling with triamcinolone acetonide led to the best treatment outcomes for alopecia areata compared to other methods of trans-epidermal drug delivery.
May 2022 in “Dermatology practical & conceptual” This study developed new graded visual scales integrating macroscopic and trichoscopic images for assessing the severity of androgenetic alopecia in men and women, potentially aiding in more objective disease evaluation.
8 citations
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October 2017 in “Dermatology practical & conceptual” This study found that a spermidine-based nutritional supplement increased the number of anagen phase hair follicles in healthy humans, suggesting potential benefits for hair loss conditions.
32 citations
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July 2017 in “Dermatology practical & conceptual” This study is the first to describe a mixed pattern of essential syphilitic alopecia using trichoscopy, identifying features like tapered bended hairs and perifollicular hyperkeratosis in a patient without secondary syphilis symptoms.
14 citations
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April 2017 in “Dermatology practical & conceptual” This study reports that yellow dots in a higher number per field of vision were the most consistent dermoscopic finding in severe cases of alopecia areata.
6 citations
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July 2015 in “Dermatology practical & conceptual” This study found that scalp necrosis in hair restoration procedures primarily occurs in the central region, particularly on the right parietal aspect, and proposed a method to prevent this complication.
4 citations
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January 2016 in “Dermatology practical & conceptual” This report describes the first known case of Kaposi's varicelliform eruption occurring after a follicular unit extraction procedure, possibly linked to surgical trauma and post-surgical steroid use.
25 citations
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August 2010 in “Acta Biomaterialia” This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.
This study introduces a new type of tissue micromodule, the micro tissue precursor (μTP), which can form complex 3D tissues, including lung stroma and skin models supporting hair viability.
March 2006 in “Chinese journal of plastic surgery” This study found that microencapsulated dermal papilla cells implanted into mice ears led to the successful regeneration of hair follicles, with APA microencapsulations of 400µm diameter allowing effective nutrient exchange.
45 citations
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November 2022 in “Acta Biomaterialia” This study developed a biomimetic 3-D co-culture system that enhances the hair-inductive properties of human dermal papilla cell aggregates, potentially improving hair follicle tissue engineering.
25 citations
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April 2008 in “Archives of Dermatological Research” This study found that transplanted microencapsulated dermal papilla cells in rat footpads can regenerate hair follicles and sebaceous gland structures, suggesting a potential substitute for fresh dermal papillae cells.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
November 2024 in “Journal of Investigative Dermatology” ATP-sensitive potassium channels are important for hair growth.
18 citations
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October 2021 in “Journal of Advanced Research” This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.
61 citations
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January 2013 in “International Journal of Biological Macromolecules” This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.
62 citations
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February 2016 in “ACS Applied Materials & Interfaces” This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.
17 citations
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April 2022 in “Bioactive Materials” This review discusses the current techniques for engineering microtissues, emphasizing the potential of continuous microfluidic processes to facilitate large-scale production, but reports no new experimental results.
68 citations
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August 2014 in “Stem Cells Translational Medicine” This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.
40 citations
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June 2013 in “Biomaterials” This study developed a 3D engineered hair follicle model that mimics the native hair bulb and may aid in drug screening for hair growth therapies.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
August 2023 in “Cell Proliferation” This study observed that incorporating human follicle dermal papilla cells into fibrin microgels increased cell viability and the formation of hair follicle structures in in vitro skin cultures compared to traditional dermal papilla spheroids, suggesting a promising approach for hair follicle regeneration therapies.
6 citations
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January 2020 in “Methods in molecular biology” This study outlines a method for isolating dermal papilla cells from human hair follicles, which may help overcome challenges in studying their role in hair growth.
April 2017 in “Plastic and reconstructive surgery. Global open” In this study with a rat muscle defect model, decellularized muscle matrix demonstrated better integration, neovascularization, and myogenesis compared to commercially available acellular dermal matrices, and also showed trends toward reduced inflammation and fibrosis after 30 and 60 days.
January 2025 in “SSRN Electronic Journal” January 2008 in “Journal of Practical Medical Techniques” This study found that microencapsulated dermal papillae cells induced hair follicle regeneration in rat ears, differing from normal follicles in configuration, size, number, and differentiation degree.
June 2014 in “Biotechnology and Bioprocess Engineering” This study demonstrated that injecting reconstructed dermal papilla-like tissues in mice led to new hair growth, suggesting potential future applications in hair transplantation and baldness treatment.
January 2006 in “Chinese Journal of Dermatology” This study found that cultured dermal papilla cells can induce hair follicle regeneration and sustain hair growth both in vivo and in vitro, with their effectiveness linked to specific protein expression levels.