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Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

KGF and activin are crucial for skin healing and repair.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

New treatments targeting specific genes show promise for treating keratin disorders.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.