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Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Sebocytes play a key role in controlling androgen levels in human skin.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Finasteride safely lowers DHT levels without affecting testosterone.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Too much androgen can cause hair loss; finasteride may help.

Androgens, like testosterone, are crucial for early testicular descent in rats.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.