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BMP signaling controls hair growth and skin color.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Targeting colon cancer stem cells might lead to better treatment results.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Apoptosis is essential for human skin development and forming a functional epidermis.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

Noggin is necessary to start the hair growth phase in skin after birth.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Blocking JAK-STAT signaling can lead to hair growth.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.