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Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Early NAS level changes affect alcohol consumption vulnerability.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Noggin is necessary to start the hair growth phase in skin after birth.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.

Hair follicle damage happens during hair transplants and can impact success; better surgical methods are needed.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

ECOHAIR® lotion is effective and safe for improving hair growth and reducing hair loss.

Women with PCOS have lower amylin levels, which are not related to their body weight.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Genetic defects and UV radiation cause skin damage and aging.

The Hairless gene is crucial for healthy skin and hair growth.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Too much androgen can cause hair loss; finasteride may help.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.