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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

RTA 408 cream protects mice from radiation skin damage.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.