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    1. Downregulation of Sonic hedgehog signaling induces G2‐arrest in genital warts Skin Research and Technology · 2022 · 4 citations
    2. Down-regulation of genes related to photoaging and inflammation in UVBirradiated mice premature skin photoaging by linoleic acid-rich tempeh oil Food Research · 2019 · 1 citations
    3. Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK / STAT1 signaling pathway FEBS Open Bio · 2025
    4. Down-Stream molecular Responses to Volatile Signaling in Roots 2021
    5. Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet Journal of Hard Tissue Biology · 2024
    6. Downregulation of Lhx2 Markedly Impairs Wound Healing in Mouse Fetus Biomedicines · 2022
    7. Downregulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors International Journal of Cosmetic Science · 2004
    8. Frequent downregulation of DMBT1 and galectin‐3 in epithelial skin cancer International Journal of Cancer · 2003 · 48 citations
    9. PKC downregulation upon rapamycin treatment attenuates mitochondrial disease Nature metabolism · 2020 · 26 citations
    10. Minoxidil downregulates Interleukin-1 alpha gene expression in HaCaT cells International Journal of Trichology · 2018 · 16 citations
    11. Androgens downregulate BMP2 impairing the inductive role of dermal papilla cells on hair follicle stem cells differentiation Molecular and Cellular Endocrinology · 2020 · 6 citations
    12. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    13. Sp6 downregulation of follistatin gene expression in ameloblasts Journal of medical investigation · 2008 · 28 citations
    14. Hairless down-regulates expression of Msx2 and its related target genes in hair follicles Journal of dermatological science · 2013 · 14 citations
    15. SIRT1 downregulation provokes immune-inflammatory responses in hair follicle outer root sheath cells and may contribute to development of alopecia areata Journal of Dermatological Science · 2023 · 13 citations
    16. Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells Clinical, Cosmetic and Investigational Dermatology · 2021 · 1 citations
    17. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    18. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    19. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    20. The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells Nature Communications · 2021 · 50 citations
    21. JAK inhibition decreases the autoimmune burden in Down syndrome eLife · 2024 · 18 citations
    22. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    23. Proprietary Herbal Extract Downregulates the Gene Expression of Il-1 and #945; in HaCaT Cells: Possible Implications Against Nonscarring Alopecia Medicinski arhiv · 2018 · 7 citations
    24. JAK inhibition decreases the autoimmune burden in Down syndrome eLife · 2024 · 2 citations
    25. Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape Experimental & Molecular Medicine · 2025
    26. MiRNA-24 downregulates KLF6 affecting STAT3 protein expression and phosphorylation regulating melanogenesis in cashmere goat coat Animal Bioscience · 2025
    27. 203 Inhibin A is downregulated during chemotherapy in patients with breast cancer Ejc Supplements · 2010
    28. Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly ˜The œAmerican journal of pathology · 2012 · 22 citations
    29. Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin Frontiers in cell and developmental biology · 2020 · 6 citations
    30. Low‐Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men With Androgenetic Alopecia and Boosts Minoxidil 2% to Bring a Sustainable Hair Regrowth Activity Lasers in Surgery and Medicine · 2021 · 4 citations