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DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Early recognition and aggressive treatment can significantly improve rare ANA-negative lupus with heart and skin issues.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.

Patients with anorexia nervosa did not show a correlation between zinc levels and taste perception or the severity of their condition.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.

A woman's liver problems improved after she stopped taking spironolactone.

The patient was diagnosed with anorexia nervosa and severe malnutrition, requiring urgent refeeding and monitoring.

A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.

Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.

A girl with no hair neglect developed plica neuropathica in the hospital, lost all her hair, but it grew back.

Careful management of blood thinners is crucial for lupus patients with APS.

A Korean woman with complete hair loss regrew her hair after taking tofacitinib, with no side effects.

Doctors should consider SLE in males even if antinuclear antibody tests are negative.

A woman with complete hair loss and severe hyperthyroidism was successfully treated with azathioprine and hydroxychloroquine.

A woman with lupus improved significantly from scalp hair loss after treatment, highlighting the need to identify psoriatic alopecia in lupus patients to avoid permanent hair loss.

A young woman with visual issues and other symptoms was diagnosed with lupus and antiphospholipid syndrome, and improved with treatment.

Isoniazid can rarely cause hair loss, which is reversible after stopping the drug.