August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a 26-year-old woman with polycystic ovarian disease and advanced hair loss (Ludwig Grade III) showed reduced hair shedding and improved hair density after four sessions of platelet-rich plasma combined with microneedling, with no reported adverse effects.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a 26-year-old woman with polycystic ovarian disease and severe hair loss showed reduced hair shedding and improved hair density following four sessions of platelet-rich plasma combined with microneedling, with no adverse effects reported.
May 2021 in “IP Indian journal of clinical and experimental dermatology” This study found that combining topical 5% minoxidil with autologous PRP therapy significantly increased hair density in men with androgenetic alopecia compared to minoxidil alone, without major side effects.
9 citations
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December 2020 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma had limited efficacy in treating alopecia areata but may help restore immune balance in the affected areas.
2 citations
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March 2025 in “PNAS Nexus” In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.
This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.
September 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that using platelet-rich plasma as a storage solution in follicular unit extraction hair transplantation significantly improved hair regeneration, density, and graft quality compared to normal saline.
July 2023 in “Clinical dermatology review” This study found that intralesional triamcinolone acetonide is more effective and faster than platelet-rich plasma in promoting hair regrowth for scalp alopecia areata.
20 citations
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September 2016 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma treatment significantly increased hair diameter and density, stopped hair fall, and boosted hair growth in men with hair loss, with no reported side effects.
14 citations
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October 2017 in “European Journal of Medical Research” In this study, platelet-rich plasma injections in mice promoted hair growth and angiogenesis compared to control, as evidenced by longer hair lengths and increased vessel formation.
November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.
February 2025 in “Journal of Pharmacy And Bioallied Sciences” In this study, researchers found that autologous platelet-rich plasma injections significantly improved hair density and patient satisfaction in both male and female patients with androgenetic alopecia, with no major side effects reported.
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study reported two cases of severe multifocal alopecia areata successfully treated with a combination of topical minoxidil and intralesional platelet-rich plasma, resulting in significant hair regrowth, though further controlled trials are needed to confirm these findings.
2 citations
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June 2021 in “Bezmialem Science” This study found that using a centrifugation speed of 1800 rpm for 10 minutes is optimal for preparing platelet-rich plasma with PRPBAG®, yielding an eightfold increase in platelet concentration.
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
March 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 35 citations
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August 2016 in “Experimental Dermatology” This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.
29 citations
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May 2025 in “Polymers” This study systematically examines how smart biomaterials used with DLP technology can enhance bioprinting in tissue engineering and regenerative medicine, while also identifying current challenges and future research needs.
9 citations
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July 2019 in “Journal of cosmetic dermatology” This pilot study suggests that topical PRP may improve facial rejuvenation, with observed enhancements in collagen production and skin architecture over 8 weeks.
6 citations
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January 2018 in “Journal of Cutaneous and Aesthetic Surgery” This study concluded that ACD-A vials yielded the highest quality and quantity of platelets in platelet-rich plasma for hair rejuvenation compared to EDTA and sodium citrate.
4 citations
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January 2025 in “The Journal of Cell Biology” This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.
3 citations
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February 2025 in “Life” In this study, significant improvements in skin density and thickness, especially around the lower eyelid, were observed across all age groups using plasma fractions from a single blood draw, indicating that the therapy's effectiveness may be age-independent.
3 citations
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October 2020 in “IntechOpen eBooks” This review discusses the potential of regenerative medicine for chronic and neuro-degenerative pain conditions and reports no new clinical results; the authors note that further trials are needed to confirm its efficacy.
1 citations
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July 2025 in “Journal of Human Immunity” This study found that administering minoxidil and PGE2 to pregnant mice with 22q11.2 deletion syndrome models corrected multiple developmental anomalies, including thymus growth and parathyroid positioning, by targeting prenatal mesenchymal differentiation.
April 2022 in “Anti-cancer agents in medicinal chemistry” In this literature review, researchers compiled evidence on repurposed synthetic radioprotective agents, including metformin and simvastatin, that have demonstrated potential in mitigating the side effects of radiotherapy in cancer treatment.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
18 citations
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January 2019 in “International Journal of Trichology” This study found that PRP therapy resulted in better hair growth and patient satisfaction than minoxidil therapy in men with androgenetic alopecia over six months, and patients with higher platelet counts in PRP experienced greater improvement.
November 2025 in “Journal of Clinical Medicine” This study found that platelet-rich plasma may improve patient-reported outcomes for scar symptoms like pain and itching at six months, although no significant changes in scar appearance were observed at three months.
January 2024 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” This study found that platelet-rich plasma therapy may be a useful alternative to 5% topical minoxidil for treating androgenetic alopecia, with differences in the effectiveness and patient satisfaction outcomes observed.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.