research Hair Loss Improvement Effect of Chrysanthemum Zawadskii, Peppermint, and Glycyrrhiza Glabra Herbal Mixture in Human Follicle Dermal Papilla Cells and C57BL/6 Mice
The herbal mixture could potentially improve hair loss.
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480-510 / 1000+ results research Milestones in Photocarcinogenesis
UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.
research The Role of Nrf2 in Hearing Loss
Activating Nrf2 can help protect against hearing loss.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Valproate: Its Effects on Hair
Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.
research Does an Apple a Day Keep Away Diseases? Evidence and Mechanism of Action
Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.
research Regulation and Dysregulation of Hair Regeneration: Aiming for Clinical Application
Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
research Biomolecules of Fermented Tropical Fruits and Fermenting Microbes as Regulators of Human Hair Loss, Hair Quality, and Scalp Microbiota
Fermented papaya and mangosteen in hair care products helped prevent hair loss and improve hair thickness.
research Regulatory Effect of Cannabidiol on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells
CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
research Capryloyl Glycine And Soy Isoflavonoids In Hypertrichosis: An Experimental And Placebo-Controlled Clinical Study
The study investigated a cream with 4% capryloyl glycine and 1% soy isoflavonoids for treating hypertrichosis on the forearms of 12 Caucasian female patients. The cream significantly reduced ornithine decarboxylase 1 (ODC1) activity by 35.1%. After four months, 91.7% of patients using the cream showed improvement, with 58.3% experiencing good efficacy and 41.7% moderate efficacy, while the placebo group showed no improvement. The cream was well-tolerated, with no adverse events and good cosmetic acceptability. The study concluded that the cream effectively reduced hair growth in the tested population, but recommended further trials with more participants to confirm these findings.
research CGF Therapy: Bridging Androgenetic Alopecia Observations to Psoriasis Treatment via IL-17 Pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
research Stem-Cell Therapy in Dermatology: Challenges and Opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research Transcranial Photobiomodulation for Brain Diseases: Review of Animal and Human Studies Including Mechanisms and Emerging Trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Chemical Composition and Biological Activities of Essential Oils of Curcuma Species
Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Scarless Wound Healing: Transitioning from Fetal Research to Regenerative Healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Applications of Tea (Camellia Sinensis) and Its Active Constituents in Cosmetics
Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
The study found that ornithine decarboxylase 1 (Odc1) was regulated by the androgen receptor (AR) in skeletal muscle, with higher expression in adult male mice compared to females and younger males. Odc1 was essential for myoblast proliferation, as its inhibition reduced myoblast numbers, while overexpression increased them. AR deletion in mice led to decreased Odc1 expression, indicating direct regulation by AR. Dihydrotestosterone (DHT) also upregulated Odc1 in human myoblasts, supporting its role in proliferation. These findings suggested that androgens, through AR, contributed to greater muscle mass in males and normal muscle development, with potential therapeutic implications for enhancing muscle mass in conditions like HIV, cancer cachexia, and sarcopenia. ODC was already a target for treating hirsutism, indicating the potential for developing ODC agonists to increase muscle mass without androgen side effects.
research Female Pattern Alopecia: Current Perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods
The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research IL-36γ Drives Skin Toxicity Induced by EGFR/MEK Inhibition and Commensal Cutibacterium Acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research As a Carrier–Transporter for Hair Follicle Reconstitution, Platelet-Rich Plasma Promotes Proliferation and Induction of Mouse Dermal Papilla Cells
Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.