October 2015 in “Elsevier eBooks” Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
155 citations
,
June 2009 in “International Journal of Dermatology” This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
20 citations
,
August 2019 in “Expert Opinion on Drug Safety” This review examines the cognitive effects of medications for lower urinary tract symptoms and indicates that muscarinic antagonists, particularly oral oxybutynin, pose the highest risk for cognitive impairment.
8 citations
,
April 2015 in “Expert Review of Gastroenterology & Hepatology” This review highlights the importance of promptly addressing symptoms in patients with inflammatory bowel disease, whether they stem from disease activity, medication side effects, or related autoimmune conditions, but it reports no new findings.
2 citations
,
September 2016 in “Drug and therapeutics bulletin” This review discusses the diagnosis and management of hidradenitis suppurativa and reports no new clinical findings, highlighting a need for better evidence and treatment guidance.
19 citations
,
November 2011 This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.
1265 citations
,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” This guideline from the Endocrine Society recommends using the Rotterdam criteria for diagnosing polycystic ovary syndrome and outlines first-line treatments, emphasizing hormonal contraceptives and lifestyle intervention.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” This review discusses various treatment options for adult female acne, highlighting the need for tailored approaches due to individual patient needs and reports no clinical outcomes.
65 citations
,
March 2016 in “Lasers in Medical Science” This review found that many low-level light therapy studies report beneficial effects but often fail to provide adequate measurement details, affecting the reliability and repeatability of the research.
52 citations
,
June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
27 citations
,
December 2015 in “Mayo Clinic Proceedings” This review presents an evidence-based algorithm for managing hidradenitis suppurativa in primary care, highlighting the need for more research on treatment effectiveness and the disease's pathogenesis.
26 citations
,
January 2019 in “Expert Opinion on Investigational Drugs” This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.
24 citations
,
July 2016 in “Revue Neurologique” This review discusses treatment options for tics in Gilles de la Tourette syndrome, highlighting existing therapies and potential future advancements, but reports no new clinical findings.
22 citations
,
October 2020 in “Anais Brasileiros de Dermatologia” This consensus concluded that oral isotretinoin is highly effective for treating acne and some off-label conditions, with common adverse events being manageable and rare serious risks not contraindicating use.
14 citations
,
September 2019 in “Eye” This review discusses the evidence for using oral medications to treat central serous chorioretinopathy, highlighting eplerenone as having the most support despite a lack of robust efficacy across studies.
10 citations
,
November 2024 in “Nature Reviews Cardiology” Skin conditions can signal heart issues, highlighting the need for integrated care.
10 citations
,
May 2015 in “International Journal of Women's Dermatology” This review discusses the unique dermatologic needs and conditions affecting women of color, noting specific skin and hair conditions but reports no clinical results.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This article reviews the potential of topical minoxidil to cosmetically thicken hair in some individuals with male pattern hair loss, but it reports no new clinical results.
August 2025 in “Benha Medical Journal” This systematic review found that platelet-rich plasma significantly improved hair density and count in androgenetic alopecia patients compared to controls, with minimal adverse effects reported.
May 2024 in “Journal of drug delivery and therapeutics” This literature review suggests that platelet-rich plasma therapy shows promise for improving hair density and patient satisfaction in men with androgenetic alopecia, though standardized protocols are still needed.
January 2019 in “ARC journal of pharmaceutical sciences” This review traces the historical understanding and treatment of acne across ancient Egyptian, Greek, and Roman civilizations, but provides no new clinical findings.
February 2013 in “Journal of the American Academy of Dermatology” This case report found that intense focused skin tightening ultrasound reduced excessive underarm sweating by nearly 80% in two patients and was associated with temporary side effects like tenderness and redness.
66 citations
,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.
1 citations
,
April 2006 in “Seminars in Reproductive Medicine” This review discusses the multifactorial causes of female sexual dysfunction and reports no clinical results; it emphasizes the need for thorough evaluation before considering androgen therapy.
121 citations
,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
117 citations
,
February 2017 in “American Journal of Clinical Dermatology” This systematic review concluded that the support for using spironolactone at commonly prescribed doses is based on evidence of limited quality.
95 citations
,
February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
84 citations
,
August 2023 in “Drugs” This article describes the development milestones and recent approvals of ritlecitinib for treating severe alopecia areata, with approvals in the USA and Japan and ongoing regulatory reviews in other regions.
61 citations
,
January 2017 in “Human Reproduction Open” This review discusses hormone replacement therapy for women with premature ovarian insufficiency, strongly recommending it for symptom relief and bone protection, but notes a lack of evidence on optimal types and doses.
31 citations
,
September 2006 in “The Journal of Clinical Endocrinology & Metabolism” This article discusses the development of a transdermal testosterone patch for postmenopausal women to deliver physiological testosterone levels but reports no new clinical results, highlighting a need for long-term safety data.