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In this study, heparin was found to exert dose- and hair cycle-dependent effects on skin epithelial cells in mice, affecting hair follicle development and protein synthesis differently based on its administration method.

This study found that specific ATP-competitive TOR inhibitors (asTORis) decrease root growth in Arabidopsis thaliana in a dose-dependent manner, similar to their effects on mammalian cells.

This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.

In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.

This study found that twice-daily intradermal injections of mouse epidermal growth factor in Merino sheep resulted in dose-dependent changes in wool follicles and fibres, including induction of catagen and subsequent regeneration.

This study suggests that vitamin A may inhibit hair follicle stem cells during refractory telogen in a dose-dependent manner, based on retinyl ester levels and vitamin A metabolism protein localization in mice.

This study developed a mouse model to simulate chronic radiation-induced salivary dysfunction, revealing dose-dependent saliva reduction and glandular changes, which may help advance salivary regenerative therapies.

In this study, Apricot Kernel Oil treatment in Wistar rats showed dose-dependent improvements for seborrheic dermatitis induced by DNFB, including reduced inflammation and oxidative stress and enhanced skin structure.

This study found that hypoxia-conditioned mesenchymal stem cell exosomes increased GM-CSF and decreased IL-1 expression in a dose-dependent manner in a murine model, suggesting potential for treating androgenetic alopecia.

This study evaluated the antiulcer potential of Glycyrrhiza glabra and found that its hydroalcoholic extract demonstrated dose-dependent protective effects against various ulcer models, comparable to standard drugs like omeprazole and cimetidine, by enhancing mucosal defenses and reducing stomach acid production.

This study found that ethanolic plant extract of Peperomia pellucida increased hair length in rabbits in a dose-dependent manner but did not significantly affect hair mass compared to controls.

In this study, a single oral dose of 2,3,4,7,8-pentachlorodibenzofuran in male Fischer rats led to dose-dependent toxicity, resulting in weight loss, hepatotoxicity, and mortality.

This study observed that isotretinoin has a low adverse-effect profile, with most side effects being dose-dependent and reversible, except for rare severe cases leading to discontinuation.

This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.

This study found that Mentha pulegium essential oil had a stronger protoscolicidal effect against Echinococcus granulosus in vitro than Mentha piperita, showing dose- and time-dependent effects.

This study found that the signaling peptide CLE40 and receptor proteins CLV2 and CRN regulate root meristem differentiation through two distinct, antagonistic pathways activated by CLE40 in a dose-dependent manner.

In this animal study, researchers found that cedrol, a constituent from Platycladus orientalis, significantly promoted hair growth in a dose-dependent manner in female C57BL/6 mice, surpassing results from blank control and 2% minoxidil groups over 21 days.

This study found that repeated oral intake of 0.5 or 5 mg/kg of cobalt ferrite nanoparticles induced pulmonary toxicity in rats, with dose-dependent oxidative stress and inflammation observed, but no notable toxicity was seen at a 0.05 mg/kg dose.

In this study, researchers found that flavonoid glycosides extracted from Dicerocaryum senecioides leaves significantly promoted hair growth in BalB/c mice, with the shortest hair growth completion time of 19 days compared to the control's 29 days, and dose-dependent results.

In this study, ozenoxacin was found to inhibit sebum production in insulin- and 5α-DHT-differentiated hamster sebocytes in a dose-dependent manner, suggesting potential benefits in acne management by combining antimicrobial activity against C. acnes with reduced sebum production.

This systematic review found that hair loss was more frequently observed in acne patients on isotretinoin doses ≥0.5 mg/kg/d compared to those on lower doses, suggesting dose-dependent effects.

This study reported that minoxidil affects the physiology of cultured endothelial cells, including reversible suspension of cell proliferation and dose-dependent influence on cell morphology, without significantly altering protein synthesis or inhibiting cell migration.

This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.

This study found that Origanum vulgare extract significantly ameliorated finasteride-induced liver and kidney damage in mice by improving biochemical indices, reducing inflammation, and enhancing antioxidant status in a dose-dependent manner.

In this observational study, dutasteride treatment was associated with statistically significant stabilization of frontal fibrosing alopecia compared to other systemic therapies, with a dose-dependent effect observed across the frontal and bilateral temporal hairlines.

This study found that hair tonics containing clove ethanol extract increased hair growth in rabbits, with a dose-dependent effect observed at varying concentrations of the extract.

This study found that Hydroxypinacolone Retinoate (HPR) may alleviate UV-induced skin photoaging by enhancing collagen synthesis, reducing degradation, and modulating inflammatory and oxidative responses in a dose-dependent manner.

This infographic compares the safety profiles of SH‑1, a cosmetic ingredient, which showed no systemic absorption, and PP405, an investigational drug with dose-dependent systemic uptake and potential threshold breaches, highlighting differences in safety between cosmetic and investigational substances according to this report.

In this study, topical red onion ethanol extract significantly restored cutaneous antioxidant and pro-angiogenic markers in UV-B-exposed rats, enhancing SOD and VEGF levels dose-dependently, but did not influence hair length, suggesting potential as an adjunct for hair photoaging.

This study reported that etrasimod did not achieve significant improvements in hair regrowth for moderate to severe alopecia areata at 24 weeks, although it showed a dose-dependent trend and was safe and well-tolerated over 52 weeks.