September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
6 citations,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Eyebrow reconstruction using hair follicle grafts was successful in a man with a benign hereditary disorder affecting his eyebrows.
2 citations,
January 2022 in “Stem cell biology and regenerative medicine” The book "Hair Follicle Regeneration" discusses the potential of regenerating human hair follicles or activating dormant ones as a possible cure for baldness, and the promising role of new technologies like 3D printing in this field.
14 citations,
May 2013 in “Emerging infectious diseases” Cryptococcus gattii can remain dormant in animals for over 8 years.
50 citations,
December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
45 citations,
January 2012 in “Experimental Dermatology” Human hair follicles switch between active and resting phases unpredictably.
39 citations,
January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
4 citations,
July 2014 in “Journal of Investigative Dermatology” Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.
June 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” PRP is a promising treatment for hair loss.
8 citations,
October 2018 in “Applied sciences” Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
2 citations,
August 2012 in “Cell Stem Cell” The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.
January 2018 in “Springer eBooks” Telogen effluvium is hair loss caused by disruption of the normal hair cycle.
63 citations,
April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
6 citations,
December 2011 in “Nature” The circadian clock in skin cells controls their growth and rest cycles.
3 citations,
April 2014 in “Journal of Dietary Supplements” CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.
July 2017 in “Mechanisms of development” Hox genes control hair follicle stem cell regeneration in different body regions.
April 2017 in “Journal of Investigative Dermatology” The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
7 citations,
January 2019 in “Journal of Analytical Toxicology” Tramadol and THC-COOH can be detected in hair for several months after stopping use.
7 citations,
November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
2 citations,
November 2022 in “Journal of Biochemistry and Molecular Biology” Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
202 citations,
August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
9 citations,
October 2014 in “Clinical and Experimental Dermatology” Temporary hair loss can occur after brain AVM treatment but usually regrows in 8 weeks.
5 citations,
January 2017 in “Skin appendage disorders” A man developed an allergic skin reaction from a therapy cap used for hair loss treatment.
1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
January 2016 in “Chemistry & Industry” Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.
499 citations,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.