research Retrospective Evaluation of Sex Hormones and Steroid Hormone Intermediates in Dogs with Alopecia
Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
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research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research A Comparative Study of Minoxidil-Induced Myocardial Lesions in Beagle Dogs and Miniature Swine
A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
research Effect of Minoxidil on Blood Pressure and Hemodynamics in Severe Hypertension
research Profile of the Progesterone Derivative Chlormadinone Acetate: Pharmacodynamic Properties and Therapeutic Applications
Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
research Comparison of the Effects of the K+-Channel Openers Cromakalim and Minoxidil Sulphate on Vascular Smooth Muscle
Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
research Spectrum and Burden of Dermatophytes in Children
The document concludes that terbinafine is effective for treating scalp fungal infections in children and recommends not excluding them from school during treatment, while also highlighting the need for updated treatment guidelines due to changing infection patterns.
research The Cascading Pathogenic Consequences of Sarcoptes Scabiei Infection That Manifest in Host Disease
Sarcoptes scabiei infection causes significant health and behavior changes in wombats.
research Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection
Minoxidil protects heart and improves recovery.
research Natural Pathogens of Laboratory Animals and Their Effects on Research
Fungal infections in lab animals can interfere with research.
research Reversible Decreases of Fertility in Male Sprague-Dawley Rats Treated Orally with Finasteride, a 5α-Reductase Inhibitor
Finasteride temporarily lowers male rat fertility without affecting libido.
research Review of Cardiovascular Findings in Humans Treated with Minoxidil
Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
research Treatment of Hirsutism with 5α-Reductase Inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research Cardiac Morphologic Alterations in Acute Minoxidil Cardiotoxicity in Miniature Swine
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research Cross-Species Sensitivity to a Novel Androgen Receptor Agonist of Potential Environmental Concern, Spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research Complications in Hair Restoration Surgery
Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.
research Hair Growth Effect of Minoxidil
Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.
research Potassium Channel Openers: Therapeutic Potential in Cardiology and Medicine
Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Cloning, Expression, and Characterization of Rhesus Macaque Types 1 and 2 5alpha-Reductase: Evidence for Mechanism-Based Inhibition by Finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research Differential Effects of Propranolol on Heart Rate and Plasma Renin Activity in Patients Treated with Minoxidil
Propranolol affects heart rate and renin levels in minoxidil-treated patients.
research A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment
Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Ovarian Hormones and Adrenal Androgens During a Woman's Life Span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil
These drugs cause hair growth without affecting testosterone or adrenal hormones.
research The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study
Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
research Alopecia in Rhesus Macaques Correlates with Immunophenotypic Alterations in Dermal Inflammatory Infiltrates Consistent with Hypersensitivity Etiology
Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.