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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

SIPHL1 from tomato enhances plants' response to low phosphate levels.

Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.