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This study highlights the potential of ZDHHC17 methylation as a biomarker or therapeutic target in addressing skin aging, offering new insights into its molecular mechanisms.

The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.

This study found that androgen/androgen receptor signaling accelerates premature senescence in dermal papilla cells, highlighting a potential target for treating androgenetic alopecia.

This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.

This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.

This study found that transient mtDNA double strand breaks in mice accelerated aging in certain tissues through increased reactive oxygen species, independent of p21/p53 pathway mediation.

This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.

This study discovered a novel interaction between the vitamin D receptor and LEF1, essential for normal Wnt signaling in keratinocytes, which is crucial for regular hair cycling.

In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.

This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.

This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.

This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.

This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.

This study found that DNA strand segregation in multipotent hair follicle stem cells occurs randomly during development and tissue homeostasis, challenging the immortal strand hypothesis.

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

In this study, researchers found that cepharanthine significantly inhibited HSV-1 replication in vitro by interfering with specific signaling pathways, arresting the cell cycle, and inducing apoptosis in infected cells, highlighting its potential as an antiviral agent.

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

This research found that Foxc1 transcription factor and COL17A1 are critical in regulating quiescence and hair thinning in hair follicle stem cells, with aging-related DNA damage leading to hair loss.

This study suggests an association between DNA methylation changes in hair follicles and inherited color dilution in Rex rabbits, contributing to a deeper understanding of epigenetic influences on rabbit pigmentation.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

This study found that the circadian clock in mouse skin regulates cell proliferation and affects sensitivity to UVB-induced DNA damage, with potential implications for understanding human skin cancer risk.

This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.

This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.

This study found that combined loss of Atr and p53 in adult mice led to severe tissue degeneration and delayed regeneration due to the accumulation of highly damaged cells.

This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.

This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.

This paper reviews the role of the telomere-telomerase system in cellular ageing and cancer, discussing potential therapies but reporting no new experimental results.

This review discusses epigenetic mechanisms in tissue repair across species and summarizes recent CRISPR-based technologies as promising tools for studying and enhancing tissue regeneration, but reports no new experimental results.

This study found that proton minibeam radiotherapy demonstrated a potential tissue-sparing effect in epidermis models by spatially confining DNA damage, suggesting reduced side effects in radiotherapy.