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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

A new painless method to collect hair follicles helps study DNA damage and aging.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

Specialized ribosomes affect aging in human skin cells.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.

Certain bacteria can boost lentil growth and improve soil used for farming.

Father's finasteride use may affect son's fertility and testicular function.

Better hair loss models needed for research.

Tempeh oil rich in linoleic acid may protect against skin aging caused by UV light.

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.