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The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Sulforaphane from broccoli can help protect skin from sun damage.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

New treatments for skin and hair repair show promise, but further improvements are needed.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

FLRG and follistatin have different roles in wound healing.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Special fiber materials boost the healing properties of certain stem cells.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

3% hydrogen peroxide does not reduce hair graft survival compared to saline.

3% hydrogen peroxide does not harm hair graft survival compared to saline.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.