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Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.

Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

KGF and activin are crucial for skin healing and repair.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

A new painless method to collect hair follicles helps study DNA damage and aging.

Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

Non-immune factors play a significant role in alopecia areata.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.