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Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Vitamin D receptor may help protect against UV-induced skin cancer.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

EGFR helps control how hair grows and forms without needing p53 protein.

When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

KGF and activin are crucial for skin healing and repair.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.