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This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoic acid were associated with decreased methylation and clinical improvement.

Skin aging reflects overall body aging and can indicate internal health conditions.

In this study using C57BL/6 mice, the researchers observed that combining minoxidil with exosomes and DNA polynucleotides improved hair follicle density and promoted gene expression linked to hair growth, suggesting enhanced hair growth potential over minoxidil alone.

This study found that lncRNA2919 negatively impacts hair follicle regeneration by decreasing follicle depth and density in a rabbit model, suggesting a regulatory role in the hair follicle cycle through DNA methylation.

This study highlights a comprehensive approach for authenticating and assessing the quality of herbal medicines using a combination of physiological, morphological, and molecular techniques, including HPTLC, ICP-MS, UV spectroscopy, and DNA barcoding, to ensure the standardization of herbal medicinal products, particularly Eclipta alba.

This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.

This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.

This study suggests that programmed cell death plays a crucial role in shaping the structure of the human epidermis and its appendages during development.

This study found that the circadian clock in mouse skin regulates cell proliferation and affects sensitivity to UVB-induced DNA damage, with potential implications for understanding human skin cancer risk.

This study discovered that the circadian clock influences hair follicle regeneration, making hair grow faster in the morning and causing more radiation-induced hair loss in the morning compared to the evening.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

This study found that combined loss of Atr and p53 in adult mice led to severe tissue degeneration and delayed regeneration due to the accumulation of highly damaged cells.

This review examines experimental and clinical evidence on PDRN, a drug derived from salmon DNA that acts via the adenosine A2A receptor and shows promise for tissue repair and treatment of diabetic foot ulcers in regenerative medicine.

This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.

This study in cashmere goats found that DNA methylation levels were lower during hair follicle differentiation compared to induction, suggesting it plays a critical role in gene regulation for hair morphogenesis.

This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.

This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.

This study identified aging-related epigenetic and transcriptomic biomarkers and suggested that curcumin might target and inhibit the JUN gene, implicating potential therapeutic strategies against aging.

This study observed that a topical liposome formulation of a 5‐α‐reductase inhibitor effectively reduced the size of treated sebaceous glands and induced apoptosis in a hamster model, suggesting potential benefits for acne treatment.

This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.

This study suggests that low proliferation rates in bald areas of androgenetic alopecia patients, along with persistent inflammatory infiltrate, may lead to follicular miniaturization and fibrosis.

This study found that a combination of oral compounds improved metabolic activity, cell viability, and proliferation in hair follicular keratinocytes, with L-cystine playing a key role in protection against oxidative stress.

This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.

In this article, researchers explored how blue light exposure affects the scalp and hair follicles, highlighting oxidative stress and hair growth disruptions, while emphasizing the importance of protective strategies like antioxidants and limiting light exposure.

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

This study found that maternal early-pregnancy serum ferritin concentrations were associated with lower DNA methylation levels at specific CpG sites in cord blood, with some associations persisting into childhood.

This study found that long-lived proteins in mice, identified across various tissues, may be linked to neurodegenerative and cardiovascular diseases due to their low renewal rate and increased risk of damage.

This thesis explores both environmental and genetic factors in prostate cancer, focusing on surrogate hormone markers, medical radiation, family history, and genetic polymorphisms related to DNA repair and hormone marker genes, but reports no new clinical findings.

This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.

This study found that topical ginsenoside Rg1 may protect skin from UVB-induced damage in mice by reducing pathological changes and modulating cytokine mRNA expression associated with inflammation and immune response.