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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fullerenes show potential in skin care but need more safety research.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Tacrolimus is an effective treatment for several skin conditions with fewer side effects than cyclosporine.

Peanut allergies can be transferred through organ transplants.

Cosmeceuticals are popular for their skin health benefits and anti-aging effects.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Higher minoxidil dose helps hair growth in non-responders without side effects.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.

Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.

Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.