research Modeling the Onset of Senescence-Associated Secretory Phenotype Predicts Therapeutic Targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
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690-720 / 1000+ results research Dietary Selenium Deprivation Oppositely Impacts Longevity and Healthspan in Telomere Dysfunctional Mice
Low selenium levels worsen health but increase lifespan in mice.
research FGF18 Signaling Determines Radioresistance of Telogen Hair Follicles by the Arrest of Hair Cycling
FGF18 helps hair follicles resist radiation by stopping hair growth cycles.
research Epigenetic and Environmental Regulation of Skin Appendage Regeneration
Both changes in genes and environmental factors like diet and toxins can significantly affect the growth of skin appendages like hair, but how these factors interact is still unclear.
research Skin Care Properties of Grape Seed Polyphenols, a By-Product of the Winery Industry
Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
research Systemic Lupus Erythematosus: Vasculopathy/Vasculitis, Susac Syndrome, and Myasthenia Gravis
Systemic lupus erythematosus is an autoimmune disease causing diverse symptoms and major organ involvement.
research Non-Competitive Androgen Receptor Inhibition In Vitro And In Vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
research UV Radiation, Vitamin D, and Epidermal Carcinogenesis
Vitamin D may help protect against nonmelanoma skin cancer.
research Loss of Stem Cells Correlates with Premature Aging in Animal Study, Penn Researchers Find
Removing a key gene in mice leads to premature aging and loss of stem cells.
research Experimental Study on the Effects of Spironolactone on Human Hair Follicles In Vitro
Spironolactone does not change hair growth.
research Effect of Ginseng Extract on the Follicular Growth of C57BL/6J Vibrissa
Ginseng extract can enhance hair growth at certain concentrations.
research Influence of Melatonin on HaCaT Cell Proliferation Measured by Means of ATP Bioluminescence and Fluorometric Assays
Melatonin affects cell growth differently based on its concentration.
research Finasteride Induces Epigenetic Modulation of LSP1: A Gene Implicated in Neutrophil Actin Dysfunction Disease
Finasteride may help treat Neutrophil Actin Dysfunction by reducing LSP1 gene activity.
research Role of Smoking in Androgenetic Alopecia: A Systematic Review
Smoking may worsen hair loss, but more research is needed.
research Epigenetic Effects of Finasteride on Human Leydig Cells
Finasteride may cause lasting sexual issues by altering specific genes in human cells.
research Antiretroviral Nucleoside and Nucleotide Analogues and Mitochondria
Some HIV treatments can harm mitochondria, potentially causing side effects like lactic acidosis and nerve damage.
research Follicular Liposomal Delivery Systems
New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Stem Cell Rejuvenation and the Role of Autophagy in Age Retardation by Caloric Restriction: An Update
Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
research Stem Cell Identification: In Vivo Lineage Analysis Versus In Vitro Isolation And Clonal Expansion
In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research The Potential Relevance of the Microbiome to Hair Physiology and Regeneration: The Emerging Role of Metagenomics
Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
research Association of mtDNA M/N Haplogroups with Systemic Lupus Erythematosus: A Case-Control Study of Han Chinese Women
The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research The Charnoly Body as a Universal Biomarker of Cell Injury
Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research The Human Hair Follicle as Sentinel for Drug Evaluation: Demonstration of Tetracycline Adhesion to Hair Follicle as Proposed Mechanism in Dysfunctional Hair Loss
Tetracycline can stick to hair follicles and potentially cause hair loss.
research Membranous Nephropathy and Lupus-Like Syndrome After Hematopoietic Cell Transplantation: A Case Report
A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.
research Epithelial Loss of Mitochondrial Oxidative Phosphorylation Leads to Disturbed Enamel and Impaired Dentin Matrix Formation in Postnatal Developed Mouse Incisor
Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.