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Melatonin protects skin against UV damage by regulating various cellular processes.

Curcumin may help reverse aging by targeting specific genes.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Loss of the Y chromosome and UTY gene activity increases cancer risk in men.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

Activated ras can protect kidney cells from a certain substance that causes cell death.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The molecule Wise is involved in the development of various structures in chick embryos.

The study created a new method to test drugs that affect hormone processing in skin.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Sex steroids affect the MafB gene differently in male and female hamsters.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.