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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The April 2016 JEADV issue covered various dermatology topics, including psoriasis, psoriatic arthritis, mTOR inhibitors, autoimmune diseases, photodynamic therapy, viral DNA in skin diseases, chronic hand eczema, and female hair loss.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Apoptosis is essential for human skin development and forming a functional epidermis.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Diet changes can protect against harmful environmental effects on fetal development.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Smoking may contribute to hair loss in men.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Effective sunscreen formulations can reduce skin absorption and enhance protection.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.

Notch signaling is essential for healthy skin and hair follicle maintenance.