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This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.

This study found that the Wnt inhibitor Dkk4 may play a role in regulating hair follicle development through a feedback loop with canonical Wnt signaling pathways.

This review discusses the mechanisms behind hair patterning during mouse embryonic development and reports no new experimental findings.

This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.

This study identified 63 genetic loci associated with male-pattern baldness, uncovering genes and pathways that may help develop treatments and suggesting its connection to other human conditions.

This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.

In this study, mouse sweat gland development relied on a regulatory sequence initiated by Wnt/β-catenin signaling, and disruptions in Wnt, Eda, or Shh pathways led to distinct developmental failures.

This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.

This study found that minor ginseng saponin F2 may promote hair growth more effectively than finasteride by enhancing anagen induction and modulating the Wnt signaling pathway in cell and mouse models.

This review outlines the adverse effects of glucocorticoid excess on bones, adipose tissue, brain, and skin, with a focus on the Wnt/β-catenin pathway, and reports no new research findings.

In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.

This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.

This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.

Wnt signaling affects the development and growth of Langerhans cells in mice.

This study found that linoleic acid from Malva verticillata seed extracts may promote hair follicle cell growth and counteract hair loss signaling in a lab setting.

This study found that ruxolitinib modulated inflammatory changes and stimulated growth factor signals by blocking the JAK-STAT pathway in an in vitro model of alopecia areata.

This study found that Polygonum multiflorum extract may promote hair growth by increasing anagen duration and activating dermal papilla cells in human hair follicles, as observed in cultured cell models.

This review explores how epidermal stem cells contribute to the development and maintenance of various skin structures, and highlights specific markers and proteins associated with these cells, but reports no new clinical results.

This study observed that certain herbal extracts may promote hair growth and inhibit hair loss in cell lines by affecting specific protein expressions similarly to minoxidil.

This study found that L-ascorbic acid 2-phosphate could reduce DHT-induced DKK-1 expression in balding scalp cells, suggesting potential for treating androgen-driven hair loss.

This study found that the vitamin D receptor, but not its ligand, regulates genes involved in hair cycle progression, suggesting a role in integrating hormone signaling pathways for hair and epidermal functions.

This study found that human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) significantly prevented hair loss induced by dexamethasone in a mouse model and enhanced cell proliferation in human hair follicle cells, suggesting a protective effect against stress-related hair loss.

This study found that mycophenolate may stabilize β-catenin and counteract interferon-γ-induced catagen changes in human dermal papilla cells, which could promote hair growth.

This study identified four immune-related signaling molecules (LGR5, PTN, JAG1, and DKK1) associated with keloid, suggesting their potential role in its pathogenesis and as targets for new treatments.

In this laboratory study, Camellia japonica fruit shell extract showed potential to mitigate hair loss by promoting hair cell growth and reducing harmful effects of DHT and oxidative stress.

This study found elevated tissue levels of DKK-1 in patients with both androgenetic alopecia and alopecia areata compared to controls, suggesting DKK-1 as a potential therapeutic target for these conditions.

This review discusses recent advancements in Wound Induced Hair Neogenesis in mice, emphasizing the potential of neogenic hair regeneration to enhance understanding of adult mammalian regeneration, but reports no new experimental results.

This study found that both androgenetic alopecia and alopecia areata showed significantly increased DKK-1 expression, potentially implicating it in the pathogenesis and as a treatment target for these conditions.

This study found that transient non-lethal levels of endogenous ROS in cultured human hair follicles promoted entry into the growth phase by activating the hair follicle stem cell niche.

This study found that dutasteride affected spinal bone formation in curdlan-treated SKG mice, while DHT treatment reduced osteoblast differentiation in vitro, suggesting that DHT inhibition might unexpectedly increase spinal ankylosis progression in ankylosing spondylitis patients.