8 citations
,
January 2017 in “Journal of Biological Chemistry” This study found that astrotactin-2 undergoes unique intramembrane proteolysis during maturation, revealing specific transmembrane topologies and substrate sequence requirements for cleavage.
5 citations
,
November 2022 in “Diversity” This review highlights the potential of indigenous southern African foods rich in phytochemicals and soluble dietary fibers to combat cardiovascular disease in economically disadvantaged urban populations in South Africa by improving dietary diversity and affordability.
March 2024 in “Clinical, cosmetic and investigational dermatology” This study found that in healthy adult women, a collagen and antioxidant-rich treatment significantly improved skin elasticity, hydration, texture, and reduced wrinkles and hair fall over 56 days compared to a placebo, indicating its efficacy and safety.
86 citations
,
April 2009 in “Journal of anatomy” This paper reviews the evolution of skin appendages and keratin-associated proteins among amniotes, proposing a model for their genetic divergence without new experimental results.
6 citations
,
May 2022 in “Medicina-lithuania” This review discusses ischemia-modified albumin as a potential new marker of oxidative stress in dermatological diseases but reports no new clinical findings.
1 citations
,
January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
May 2026 in “International Journal of Molecular Sciences” In this study, a new formulation of human placental extract showed antioxidant and neurite outgrowth activities, significantly reduced hair graying in mice, and alleviated neuropathy symptoms, suggesting potential therapeutic benefits.
March 2026 in “International Journal of Cosmetic Science” This research reports that KCV and its palmitoylated derivatives show strong effectiveness in strengthening hair proteins, indicating their potential for use in advanced hair care products.
December 2025 in “Biopolymers” This study found that chemically treated hair, particularly when subjected to both acid straightening and bleaching, experiences more significant structural damage when exposed to heat, highlighting key changes in both the internal and surface components of hair fibers.
December 2025 in “International Journal of Molecular Sciences” This study found that an aqueous extract of Bacopa procumbens improved motor function and preserved neuronal structure in a mouse model of Parkinson's disease, suggesting its neuroprotective potential.
August 2025 in “Applied Sciences” This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.
January 2025 in “Biomaterials Research” This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.
February 2024 in “International journal of molecular sciences” This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.
January 2024 in “Journal of cosmetic dermatology” This study found that Silibinin-loaded polymeric micelles significantly protected human hair from UV-B induced structural and chemical damage by preventing increases in roughness and reducing protein loss.
February 2023 in “Molecules” In this study, N. ottonis cactus cell extract applied to mice promoted hair growth and increased the number of hair follicles, suggesting its potential as a hair-growth-promoting agent.
37 citations
,
October 2015 in “PeerJ” This study found that shampoo and conditioner do not alter hair's molecular structure, while perming treatments significantly affect keratin and intermediate filament structures due to bond alterations.
November 2025 in “Journal of Clinical Medicine” This study found that a novel drinkable supplement significantly increased hair density and reduced hair shedding over six months in women with telogen effluvium, although the authors emphasize the need for larger, placebo-controlled trials to confirm these promising results.
73 citations
,
October 2013 in “International Journal of Cosmetic Science” This review examines the chemical composition and potential health risks of hair straighteners, but it reports no new findings and emphasizes the importance of understanding hair fibre structure for safe use.
1 citations
,
January 2024 in “Scientific reports (Nature Publishing Group)” This study explored using keratin extracted from human hair waste to create biodegradable bioplastic films, revealing promising potential for applications in packaging and disposable items due to their uniform surface morphology and ability to degrade with keratinophilic fungi.
40 citations
,
June 2013 in “Journal of cosmetic dermatology” This review discusses the widespread use of Brazilian keratin treatments and notes that many contain formaldehyde, marketed as safe despite potential safety concerns, but reports no new clinical results.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that specific immune cell phenotypes, particularly CD25 on CD4 Treg cells, were causally linked to androgenic alopecia, suggesting potential targets for immune-based therapies.
40 citations
,
July 2015 in “Journal of Cellular Biochemistry” This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.
May 2026 in “International Journal of Nanomedicine” This review discusses the promising roles of nanozymes in burn wound treatment, highlighting their broad enzyme-like activities that include antibacterial, anti-inflammatory, and pro-angiogenic effects, along with advantages over traditional treatments such as reduced drug resistance and higher stability.
May 2025 in “Journal of Experimental Pharmacology” This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders.
18 citations
,
February 2023 in “PLoS ONE” This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.
January 2024 in “Seven Editora eBooks” This paper reviews various techniques for measuring the physical and mechanical properties of human hair fibers, emphasizing their importance in developing effective cosmetic products.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.
226 citations
,
January 2002 in “Biological and Pharmaceutical Bulletin” This study developed a rapid method to extract proteins from human hair, revealing phosphorylation on serine and threonine residues in alpha-keratins and matrix proteins.
83 citations
,
July 2008 in “Current Opinion in Chemical Biology” This review discusses the structural and functional advances in understanding sulfotransferases and sulfatases, highlighting new insights into enzyme mechanisms and inactivation by clinically relevant aryl sulfamates, but provides no new experimental results.
71 citations
,
August 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study revealed that human keratin-associated protein genes are expressed in specific patterns in hair fiber regions and vary in size, with some variations distinct across different populations.